Because of the global spread of Zika virus, accurate and high-throughput diagnostic immunoassays are needed. We compared the sensitivity and specificity of 5 commercially available Zika virus serologic assays to the recommended protocol of Zika virus IgM-capture ELISA and plaque-reduction neutralization tests. Most commercial immunoassays showed low sensitivity, which can be increased.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5572859PMC
http://dx.doi.org/10.3201/eid2309.162043DOI Listing

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