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An atypical presentation of Paget's Disease of the breast without nipple involvement: Case report and review of the literature. | LitMetric

AI Article Synopsis

  • A 63-year-old Caucasian woman developed a right breast skin lesion that was diagnosed as Paget's Disease of the breast (PDB), which was separate from the nipple.
  • Imaging tests showed no signs of underlying breast cancer or nipple involvement.
  • The patient had a segmental mastectomy that preserved the nipple, and pathology confirmed residual PDB without any additional breast cancer, marking this as the first known case of isolated PDB without nipple involvement.

Article Abstract

We present a case of a 63 year-old Caucasian female who developed a right breast skin lesion discrete from the nipple that was subsequently diagnosed as Paget's Disease of the breast (PDB). Imaging did not reveal an underlying breast cancer or involvement of the nipple. The patient underwent a segmental mastectomy preserving the nipple and final pathology demonstrated residual Paget's disease of the skin and did not reveal any additional underlying breast carcinoma. To our knowledge, this case represents the first reported diagnosed case of isolated PDB without nipple involvement.

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Source
http://dx.doi.org/10.1016/j.prp.2017.06.002DOI Listing

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