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[Diagnosis and treatment of gastrointestinal bleeding after kidney transplantation].

Beijing Da Xue Xue Bao Yi Xue Ban

October 2024

Department of Urology, The First Affiliated Hospital of Anhui Medical University; Institute of Urology, Anhui Medical University; Anhui Province Key Laboratory of Urological and Andrological Diseases Research and Medical Transformation, Hefei 230022, China.

Objective: To analyze the clinical characteristics of acute and chronic gastrointestinal bleeding in patients with end-stage renal disease (ESRD) after kidney transplantation, to improve the understanding of the causes, diagnosis, treatment and prevention of this complication, and to improve the management of patients with gastrointestinal bleeding after kidney transplantation.

Methods: The clinical, imaging and pathological data of patients with gastrointestinal bleeding after kidney transplantation in the Department of Urology of The First Affiliated Hospital of Anhui Medical University from August, 2015 to December, 2020 were collected. The etiology, early clinical manifestations, abnormal laboratory tests and examinations, treatment procedures, late prevention and treatment measures and outcomes of gastrointestinal bleeding were retrospectively studied, and the relevant literature was summarized and reviewed.

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Solid pseudopapillary neoplasms (SPNs) of the pancreas are rare tumours with distinctive clinicopathological features. We present a case of a 51-year-old female with a large cystic neoplasm involving the entire pancreas, initially presenting with abdominal pain. Diagnostic imaging revealed a well-defined heterogeneously enhancing mixed solid cystic lesion in the pancreas.

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Article Synopsis
  • Some patients with familial adenomatous polyposis (FAP) require total duodenectomy due to extensive polyposis or cancer, with a need for ongoing endoscopic monitoring of the jejunum and stomach post-surgery.
  • In a study involving 119 patients, 41% developed jejunal adenomas after surgery, particularly those who had pancreas-preserving total duodenectomy (PPTD), while 30% were found to have gastric adenomas.
  • The findings emphasize a significant risk of developing adenomas and cancers in the remaining gastrointestinal tract after surgery, underscoring the importance of regular surveillance to manage potential complications and poor cancer prognosis.
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In selected patients with metastatic renal cell carcinoma, metastasectomy can achieve prolonged survival. Herein we report a patient with concomitant pancreatic and duodenal metastases occurring 12 years after total right nephrectomy for a renal cell carcinoma. The metastases were successfully treated by a pancreas-sparing duodenectomy and distal pancreatectomy.

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