[This corrects the article DOI: 10.1371/journal.pone.0173917.].
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Metab Eng
March 2025
State Key Laboratory of Microbial Metabolism, Joint International Research Laboratory of Metabolic & Developmental Sciences, School of Life Sciences and Biotechnology, Shanghai Jiao Tong University, 800 Dong-chuan Road, Shanghai, 200240, China. Electronic address:
Correct folding of endoplasmic reticulum (ER)-localized membrane proteins, such as cytochrome P450, endows a synthetic biology host with crucial catalytic functions, which is of vital importance in the field of metabolic engineering and synthetic biology. However, due to complexed interaction with cellular membrane environment and other proteins (e.g.
View Article and Find Full Text PDFComput Struct Biotechnol J
February 2025
Faculty of Dentistry, The University of Hong Kong, Hong Kong, China.
Despite extensive research on the gut bacteriome during infancy and its correlation with various chronic diseases, the influence of diet on gut mycobiome development in infants remains unexplored. To address this significant research gap, we conducted a study on 70 healthy Hong Kong Chinese infants who were either directly breastfed, expressed milk-fed, or formula-fed. Our analysis revealed that formula-fed infants had higher fungal diversity and composition in their gut mycobiome compared to those in breastfed and expressed milk-fed infants.
View Article and Find Full Text PDFCommun Biol
March 2025
Institute of Molecular Biology, Biocenter, Medical University Innsbruck, Innsbruck, Austria.
Iron homeostasis is key to both the survival of virtually all organisms and the virulence of fungi including Aspergillus fumigatus, a human fungal pathogen causing life-threatening invasive infections. Unlike the extensively studied fungal species Saccharomyces cerevisiae and Schizosaccharomyces pombe, A. fumigatus encodes an uncharacterized homolog of vertebrate ferroportin (Fpn1), termed FpnA.
View Article and Find Full Text PDFJ Dairy Res
March 2025
Pishgam Damparvar Sepahan Co., Isfahan, Iran.
Meeting the buffer requirements of concentrate-fed dairy cows is a challenging task. We evaluated the effect of supplementing different feed additives to diets containing KCO on feed intake, nutrient digestion and milk production of dairy cows. Eight peak lactation high yielding Holstein cows were used in a replicated 4 × 4 Latin square design with 4 periods of 21 d (14 d for diet adaptation and 7 d for sampling and data collection).
View Article and Find Full Text PDFExpert Rev Anti Infect Ther
February 2025
Department of Gastroenterology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Introduction: The diagnosis and management of abdominal tuberculosis, i.e Gastrointestinal Tuberculosis (GITB) and tuberculous peritonitis (TBP) is challenging. Abdominal tuberculosis, presenting usually with abdominal pain, intestinal obstruction, and constitutional symptoms, is typically a paucibacillary condition.
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