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Case Report: Novel Disseminated Infection in a Dog.
Front Vet Sci
May 2022
Department of Population Health and Pathobiology, College of Veterinary Medicine, North Carolina State University, Raleigh, NC, United States.
A 2.5-year-old, 25.5 kg, spayed female Australian Shepherd dog had a 2-month history of shifting leg lameness in all limbs, tetraparesis, progressive lethargy, and severe pain.
View Article and Find Full Text PDFNovel Penicillium species causing disseminated disease in a Labrador Retriever dog.
Med Mycol
November 2020
University of Missouri, A344 Clydesdale Hall, Columbia, Missouri, USA.
Article Synopsis
- A novel species of Penicillium, named Penicillium labradorum, was isolated from a Labrador retriever suffering from a severe disseminated fungal infection, showing clinical signs like lethargy and lameness.
- Fine-needle biopsies revealed pyogranulomatous inflammation with numerous fungal elements, leading to the classification of the isolate and further molecular testing confirming it as a new species phylogenetically distinct from related species.
- Antifungal susceptibility tests showed that the isolate was resistant to fluconazole but sensitive to other antifungals; despite treatment, the dog's condition worsened, resulting in euthanasia about 587 days post-diagnosis.
[Calcitriol induced hypercalcemia in a hunting dog with a disseminated Paecilomyces variotii infection].
Schweiz Arch Tierheilkd
May 2018
Klinik für kleine Haustiere, Fachbereich Veterinärmedizin, Freie Universität Berlin.
A 5-year old hunting dog was presented with reduced appetite, weight loss and polyuria/polydipsia. Hematology and clinical chemistry revealed anemia, leukocytosis, increased liver enzymes, hypoalbuminemia and hypercalcemia. The cytological, pathohistological and microbiological examination identified a disseminated infection with the saprophytic mould fungus Paecilomyces variotii in the biopsies of the spleen and a lymph node.
View Article and Find Full Text PDFPaecilomyces as a Cause of Lymph Nodes Enlargement in Hodgkin's Lymphoma.
Indian J Pediatr
November 2017
Department of Medical and Pediatric Oncology and Hematology, Fortis Memorial Research Institute, Gurgaon, Haryana, 122002, India.
Pathology of a mouse model of x-linked chronic granulomatous disease.
Contemp Top Lab Anim Sci
September 2002
Department of Comparative Medicine, Medical University of South Carolina, 114 Doughty Street, Charleston 29425, USA.
A colony of knockout mice (gene designation Cybb tm1) has been maintained at this institution for 5 years. These mice are lacking the b subunit of NADPH oxidase and are susceptible to experimental infection with Aspergillus fumigatus. The purpose of this study was to document the spontaneous diseases present in these mice which are a murine model of X-linked chronic granulomatous disease and to compare these lesions to those of chronic granulomatous disease in humans.
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