Small Cell Carcinoma (SCC) of the salivary gland is a rare and aggressive tumour accounting for about less than 1% of the salivary gland tumours. Submandibular gland involvement is extremely rare. These tumours frequently present with metastasis to lymph node and distant organs. We report a case of a 30-year-old male patient who presented with a swelling on the left side of the face below the jaw and the floor of the mouth. The tumour was excised followed by histopathological evaluation and diagnosed as SCC of left submandibular gland. Immunohistochemistry was positive for pan cytokeratin, synaptophysin, chromogranin, Ki-67, CK5/6, and negative for Thyroid Transcription Factor (TTF-1) which confirmed that the tumour was SCC of submandibular salivary gland.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483686PMC
http://dx.doi.org/10.7860/JCDR/2017/22341.9885DOI Listing

Publication Analysis

Top Keywords

salivary gland
16
extremely rare
8
small cell
8
cell carcinoma
8
submandibular salivary
8
submandibular gland
8
gland
6
rare case
4
case small
4
submandibular
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!