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| http://dx.doi.org/10.1093/ndtplus/sfq006 | DOI Listing |
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Hyperuricaemia and gout in the Pacific.
Nat Rev Rheumatol
March 2025
Department of Rheumatology, Saint Philibert Hospital, Lille Catholic University, Lille, France.
Gout is the most common form of inflammatory arthritis in adults worldwide. There has been a steady increase in prevalence, which varies across different geographic areas and is high in the Indigenous (First Nations) peoples of the Pacific region. Palaeo-archaeological studies demonstrate that gout was present in the Pacific region prior to European colonization, which is suggestive of genetic predisposition.
View Article and Find Full Text PDFThe Fifth Element: Is Vascular Dysfunction an Intrinsic Feature of Gout?
Semin Arthritis Rheum
February 2025
Department of Medicine, Division of Rheumatology, NYU Grossman School of Medicine And Rheumatology Section, Department of Medicine, VA New York Harbor Health Care System, NY Campus, USA.
Gout, the most common inflammatory arthritis, affects as many as 5.1% of the adult population. Classically, gout is conceived as four sequential phenotypic states: 1) asymptomatic hyperuricemia 2) acute gout flare 3) inter-critical gout (gout between flares); and 4) tophaceous gout.
View Article and Find Full Text PDFTophaceous Gout.
Clin Case Rep
February 2025
Department of General Practice (General Internal Medicine) Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College Beijing China.
Chronic untreated hyperuricemia can lead to polyarticular tophaceous gout from recurrent arthritis, which could cause bone erosion and joint damage. "Overhanging edges" on X-ray, indicative of bony erosions, are highly specific for gout. Tophaceous gout, though more common in older adults, can occur in younger individuals with prolonged hyperuricemia.
View Article and Find Full Text PDFChronic Tophaceous Gout Presenting as Carpal Tunnel Syndrome.
Int J Dermatol
February 2025
Department of Radiodiagnosis, JIPMER, Puducherry, India.
Management of gout in primary care of Hong Kong in accordance with international guidelines: any gaps to bridge?
BMC Prim Care
February 2025
Department of Family Medicine and Primary Healthcare, Kowloon Central Cluster, Hospital Authority, Queen Elizabeth Hospital, Room 807, Block S, 30 Gascoigne Road, Kowloon, Hong Kong SAR, China.
Background: The global prevalence of gout ranges from 1 to 6.8% in different countries, while around 3% in Hong Kong. Sudden elevated serum urate level (SUA) will result in acute arthritis and repeated flare-ups.
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