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http://dx.doi.org/10.1111/pedi.12535 | DOI Listing |
Animals (Basel)
December 2024
Department of Computer Engineering, Jordan University of Science and Technology, P.O. Box 3030, Irbid 22110, Jordan.
Sandflies, small insects primarily from the Psychodidae family, are commonly found in sandy, tropical, and subtropical regions. Most active during dawn and dusk, female sandflies feed on blood to facilitate egg production. In doing so, they can transmit infectious diseases that may cause symptoms such as fever, headaches, muscle pain, anemia, skin rashes, and ulcers.
View Article and Find Full Text PDFPlast Reconstr Surg Glob Open
November 2024
From the Department of Plastic, Reconstructive and Aesthetic Surgery, Brussels University Hospital (UZ Brussel), Brussels, Belgium.
Transl Psychiatry
October 2024
Department of Neurology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Substance use disorders (SUDs) imposes profound physical, psychological, and socioeconomic burdens on individuals, families, communities, and society as a whole, but the available treatment options remain limited. Deep brain-machine interfaces (DBMIs) provide an innovative approach by facilitating efficient interactions between external devices and deep brain structures, thereby enabling the meticulous monitoring and precise modulation of neural activity in these regions. This pioneering paradigm holds significant promise for revolutionizing the treatment landscape of addictive disorders.
View Article and Find Full Text PDFExp Physiol
October 2024
Healthspan, Resilience and Performance Research, Florida Institute for Human and Machine Cognition, Pensacola, Florida, USA.
Exogenous ketone supplements are a potential augmentation strategy for cognitive resilience during acute hypoxic exposure due to their capacity to attenuate the decline in oxygen (O) availability, and by providing an alternative substrate for cerebral metabolism. Utilizing a single-blind randomized crossover design, 16 male military personnel (age, 25.3 ± 2.
View Article and Find Full Text PDFAdv Healthc Mater
November 2024
Intrepid Labs Inc., MaRS Centre, West Tower, 661 University Avenue Suite 1300, Toronto, ON, M5G 0B7, Canada.
Over the last four decades, pharmaceutical companies' expenditures on research and development have increased 51-fold. During this same time, clinical success rates for new drugs have remained unchanged at about 10 percent, predominantly due to lack of efficacy and/or safety concerns. This persistent problem underscores the need to innovate across the entire drug development process, particularly in drug formulation, which is often deprioritized and under-resourced.
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