AI Article Synopsis
- The text discusses efficient methods for synthesizing tetrahalodiboranes(4) using BBr as a common precursor.
- It highlights the one-step preparation of dimethylsulfide adducts BCl(SMe) and BBr(SMe) from the commercially available B(NMe) on both small and large scales.
- These synthesis techniques open up new opportunities for utilizing tetrahalodiboranes(4) in various chemical applications.
Article Abstract
Convenient solution-phase syntheses of tetrahalodiboranes(4) BF, BCl and BI are presented herein from common precursor BBr. In addition, the dimethylsulfide adducts BCl(SMe) and BBr(SMe) are conveniently prepared in one-step gram and multigram scale syntheses from the commercially-available starting material B(NMe). The results provide simple access to the full range of tetrahalodiboranes(4) for the exploration of their untapped synthetic potential.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c7cc03148c | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Ex Situ Synthesis of N-Capped Peptides in the Solution Phase via Palladium-Catalyzed Aminocarbonylation Utilizing Chloroform-COware.
J Org Chem
January 2025
Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research, Sector 67, S. A. S. Nagar, Punjab 160 062, India.
We report the synthesis of N-capped peptides under mild conditions using the oxidative aminocarbonylation of aryl iodides and peptide esters as nucleophiles in the solution phase. Ex situ chloroform in chamber A generates CO, which diffuses to chamber B, which contains other reactants. This method offers N-capped peptides at 80 °C for 12 h.
View Article and Find Full Text PDFAsymmetric Amplification in Oxypalladation/Malononitrile Addition Cascade Enabled by Heterochiral-Assembly of Products.
Org Lett
January 2025
Hubei Research Center of Fundamental Science-Chemistry, Engineering Research Center of Organosilicon Compounds & Materials, Hubei Key Lab on Organic and Polymeric Optoelectronic Materials, and College of Chemistry and Molecular Sciences, Wuhan University, 299 Bayi Rd, Wuhan 430072, China.
An enantioselective oxypalladation/malononitrile addition cascade reaction of alkyne-tethered malononitriles was reported to synthesize enaminones bearing an all-carbon quaternary center. Using Pd(TFA)/Pyox as a precatalyst, an array of enaminone products were obtained in moderate overall yields, with excellent er (93.5:6.
View Article and Find Full Text PDFA Pyrrole-Fused Nanographene and its Edge-Perchlorinated Derivative Featuring a Corannulene Core and Five N-doped Heptagons.
Angew Chem Int Ed Engl
January 2025
State Key Laboratory for Physical Chemistry of Solid Surfaces, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials), Department of Chemistry, Xiamen University, Xiamen, 361005, China.
A pyrrole-fused analogue of warped nanographene, designated as deca-nitrogen doped 'WNG' (azaWNG), was synthesized through the annular fusion of decapyrroylcorannulene. The resulting azaWNG exhibited extremely limited solubility in common organic solvents and was characterized solely by mass spectrometry. Theoretical calculations revealed that azaWNG has a sunflower-like molecular structure with electron-deficient corannulene as the core and electron-rich pyrrole as the petals, demonstrating a significantly narrower energy gap compared to all-carbon WNG.
View Article and Find Full Text PDFIn silico design of dehydrophenylalanine containing peptide activators of glucokinase using pharmacophore modelling, molecular dynamics and machine learning: implications in type 2 diabetes.
J Comput Aided Mol Des
December 2024
Amity Institute of Biotechnology, Amity University Uttar Pradesh, Sector-125, Noida, UP, 201313, India.
Article Synopsis
- Diabetes is a significant global health issue that involves high healthcare costs and complex treatments, leading to the search for new medication options due to the side effects of current therapies.
- Glucokinase (GK) plays a crucial role in regulating blood sugar levels and has unique properties that make it a good target for type-2 diabetes treatment; glucokinase activators (GKAs) can enhance GK activity, but safety concerns persist with existing options.
- A study developed a new type of GKA using peptide-based compounds with unique amino acids, discovering three promising peptides that increase GK activity significantly; machine learning techniques were also employed to predict their effectiveness.
Dual Activities of Flower-Like Gold-Iron Oxide Nanozyme for Peroxidase-Mimicking and Glucose Detection.
Chem Asian J
December 2024
Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee, 247 667, India.
Nanozymes, constituting of inorganic nanomaterials, are the sustainable and cost-effective alternatives of the naturally abundant enzymes. For more than a decade, nanozymes have shown astonishingly enhanced enzymatic activity as compared to its naturally occurring counterpart and emerged as a potential platform in biomedical science. The current study reports a novel flower shaped gold-iron oxide nanocomposite prepared via a facile and green solution phase redox mediated synthesis.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!