Palladium-catalyzed allylation of tautomerizable heterocycles with alkynes.

Org Biomol Chem

College of Chemical Engineering, Zhejiang University of Technology, Chaowang Road 18#, Hangzhou 310014, China.

Published: July 2017

A method for the allylic amidation of tautomerizable heterocycles was developed by a palladium catalyzed allylation reaction with 100% atom economy. A series of structurally diverse N-allylic substituted heterocycles can be synthesized in good yields with high chemo-, regio-, and stereoselectivities under mild conditions.

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Source
http://dx.doi.org/10.1039/c7ob01119aDOI Listing

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