Background & Aims: Cancer cachexia is multifactorial and should be targeted using a multimodal form of intervention. The purpose of the present trial was to test the effects of a combined nutrition and physical exercise program on cancer patients with metastatic or locally advanced tumors of the gastrointestinal and lung tracts.
Methods: Patients were randomized into two groups: One group received a minimum of three standardized individual nutritional counselling sessions and participated in a 60-min exercise program twice a week. The second group received their usual care. The intervention spanned a period of three months. Quality of life (European Organization for Research and Treatment of Cancer Quality of Life Questionnaire version 3.0), physical performance (hand-grip strength, 6-min walk test, timed sit-to-stand test and 1 repetition maximum leg press), nutritional status (body weight, bioelectrical impedance analysis), dietary intake (three-day dietary record) and clinical data (unexpected hospital days, performance status) were tested at baseline and after three and six months.
Results: In total, 18 women and 40 men (mean age 63, range 32-81) with metastatic or locally advanced tumors of the gastrointestinal (n = 38) and lung (n = 20) tracts were included. Median adherence to the supervised exercise program was 75%. The median number of individual nutritional counselling sessions was 3.0 (range 0-7 sessions). Post intervention, no difference in global health status/quality of life (overall QoL) was observed. Intervention was superior to UC for the patient-rated symptom scale regarding nausea and vomiting (p = 0.023) and protein intake (p = 0.01). No statistical differences were observed for energy intake, nutritional status and physical performance.
Conclusions: The results show good adherence to a combined nutrition and exercise program. The multimodal intervention did not improve overall QoL, but contributed to an adequate protein intake and to the general well-being of the patient by reducing nausea and vomiting.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.clnu.2017.05.027 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Purpose: This study aimed to explore the potential application of NAO in guiding patients through rehabilitative exercises using external audiovisual stimuli, focusing on temporospatial control in terms of range of motion (ROM), execution time and movement smoothness.
Methods: This is a preliminary analysis involving ten healthy volunteers and two patients with shoulder musculoskeletal disorders. The protocol was developed in two phases (III and IV) with different ROM limits and including flexion-extension (FE), external-rotation (ER) and internal-rotation (IR) exercises, performed at two speeds and both with and without NAO assistance.
Seizing the Teachable Moment: A Pilot Study of Preventive Lifestyle Education in the Emergency Department.
Cureus
November 2024
Biostatistics, Michigan State University College of Osteopathic Medicine, East Lansing, USA.
Background Preventive measures are critical in avoiding and limiting the severity of diseases. Key lifestyle behaviors include sleep hygiene, habitual exercise, a healthy diet, and avoidance of risky substances, particularly the use of tobacco. The transtheoretical model (TTM) of change suggests that patients can move towards healthful changes through education.
View Article and Find Full Text PDFEvaluation of an assistive exosuit for alleviating neck and shoulder muscle fatigue during prolonged flexed neck posture.
J Neuroeng Rehabil
December 2024
Center for Healthcare Robotics, Korea Institute of Science and Technology, Seoul, 02792, Republic of Korea.
Introduction: Neck pain affects 203 million people globally and is prevalent in various settings due to factors like poor posture, lack of exercise, and occupational hazards. Therefore, addressing ergonomic issues with solutions like a wearable robotic device is crucial. This research presents a novel assistive exosuit, characterized by its slim and lightweight structure and intuitive control without the use of hands, designed to mitigate muscle fatigue in the neck and shoulders during prolonged flexed neck posture.
View Article and Find Full Text PDFEffects of the Vivifrail-B multicomponent exercise program based on society ecosystems theory on physical function in community-dwelling frail older adults: A randomized controlled trial.
Exp Gerontol
December 2024
Department of Nursing, College of Medical Science, Huzhou University, 759 Second Ring Road, Huzhou District, Zhejiang 313000, China.
Objective: The study aimed to explore the short and long-term effects of the Vivifrail-B multicomponent exercise based on society ecosystems theory on physical function in community-dwelling frail older adults.
Methods: 59 older adults were randomly assigned to the intervention (n = 30) and control (n = 29) groups. The exercise was performed thrice a week for 12 weeks, with one offline group training and two at home training.
The impact of training intervention on levels of indicator bacteria and prevalence of selected pathogens in raw milk from smallholder women dairy farmers in Central Ethiopia.
J Food Prot
December 2024
Department of Food Science and Technology, College of Food Agriculture and Environmental Sciences, The Ohio State University, Columbus, Ohio, USA.
Contamination of milk is a serious public health risk, particularly in developing countries such as Ethiopia. Training is a tool for improving the quality and safety of milk. However, its effect on the microbial quality and safety of milk has not been well documented.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!