[Compliancy of pre-exposure prophylaxis for HIV infection in men who have sex with men in Chengdu].

Zhonghua Liu Xing Bing Xue Za Zhi

Epidemiology and Biostatistics Department, West China School of Public Health. Sichuan University, Chengdu 610041, China.

Published: May 2017

AI Article Synopsis

  • The study evaluated HIV pre-exposure prophylaxis (PrEP) compliance among men who have sex with men (MSM) in Chengdu, Sichuan from July 2013 to September 2015.
  • The research involved 328 MSM split into three groups: daily PrEP, intermittent PrEP, and a control group, with follow-ups and surveys every three months.
  • Results showed a compliance rate of 41.8%, with the daily group having significantly better compliance (69%) compared to the intermittent group (14.3%), indicating that the type of PrEP significantly affects adherence.

Article Abstract

To evaluate the compliancy of HIV pre-exposure prophylaxis (PrEP) in men who have sex with men (MSM) in Chengdu, Sichuan province, and explore the influencing factors. From 1 July 2013 to 30 September 2015, a random, open, multi-center and parallel control intervention study was conducted in 328 MSM enrolled by non-probability sampling in Chengdu. The MSM were divided into 3 groups randomly, i.e. daily group, intermittent group (before and after exposure) and control group. Clinical follow-up and questionnaire survey were carried out every 3 months. Their PrEP compliances were evaluated respectively and multivariate logistic regression analysis was conducted to identify the related factors. A total of 141 MSM were surveyed, in whom 59(41.8) had good PrEP compliancy. The PrEP compliancy rate was 69.0 in daily group, higher than that in intermittent group (14.3), the difference had significance ((2)=45.29,<0.001). Multivariate logistic analysis indicated that type of PrEP was the influencing factors of PrEP compliancy. Compared with daily group, the intermittent group had worse PrEP compliancy (=0.07, 95: 0.03-0.16). The PrEP compliance of the MSM in this study was poor, the compliancy would be influenced by the type of PrEP.

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Source
http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2017.05.017DOI Listing

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