To evaluate the compliancy of HIV pre-exposure prophylaxis (PrEP) in men who have sex with men (MSM) in Chengdu, Sichuan province, and explore the influencing factors. From 1 July 2013 to 30 September 2015, a random, open, multi-center and parallel control intervention study was conducted in 328 MSM enrolled by non-probability sampling in Chengdu. The MSM were divided into 3 groups randomly, i.e. daily group, intermittent group (before and after exposure) and control group. Clinical follow-up and questionnaire survey were carried out every 3 months. Their PrEP compliances were evaluated respectively and multivariate logistic regression analysis was conducted to identify the related factors. A total of 141 MSM were surveyed, in whom 59(41.8) had good PrEP compliancy. The PrEP compliancy rate was 69.0 in daily group, higher than that in intermittent group (14.3), the difference had significance ((2)=45.29,<0.001). Multivariate logistic analysis indicated that type of PrEP was the influencing factors of PrEP compliancy. Compared with daily group, the intermittent group had worse PrEP compliancy (=0.07, 95: 0.03-0.16). The PrEP compliance of the MSM in this study was poor, the compliancy would be influenced by the type of PrEP.
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http://dx.doi.org/10.3760/cma.j.issn.0254-6450.2017.05.017 | DOI Listing |
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