The ATI score (age-thrombus burden-index of microcirculatory resistance) determined during primary percutaneous coronary intervention predicts final infarct size in patients with ST-elevation myocardial infarction: a cardiac magnetic resonance validation study. | LitMetric
Aims: The age-thrombus burden-index of microcirculatory resistance (ATI) score is a diagnostic tool able to predict suboptimal myocardial reperfusion before stenting, in patients with ST-elevation myocardial infarction (STEMI). We aimed to validate the ATI score against cardiac magnetic resonance imaging (cMRI).
Methods And Results: The ATI score was calculated prospectively in 80 STEMI patients. cMRI was performed within 48 hours in all patients and in 50 patients at six-month follow-up to assess the extent of infarct size (IS%) and microvascular obstruction (MVO%). The ATI score was calculated using age (>50=1 point), pre-stenting index of microcirculatory resistance (IMR) (>40 and <100=1 point; ≥100=2 points) and angiographic thrombus score (4=1 point; 5=3 points). ATI score was closely related to final IS% (ATI.
Background: Medical education in resource-constrained settings such as Pakistan faces significant challenges, including large class sizes, limited resources, and reliance on traditional teacher-centered pedagogies. These factors hinder effective learning and fail to equip students with the critical thinking and practical skills essential for modern medical practice. Educators play a fundamental role in shaping student experiences but often struggle to adopt student-centred methodologies due to insufficient training, resource limitations, and institutional constraints.
The study aimed to compare the effectiveness of three methods for administering atipamezole—intranasal atomization, intranasal drops, and intramuscular injection—in reversing sedation from medetomidine in healthy dogs.
A total of 40 mixed-breed shelter dogs were included, with various parameters like sedation score, heart rate, respiratory rate, and blood pressure measured at different times during the study.
Results showed that intramuscular injection led to the quickest recovery from sedation, while both intranasal methods were effective but slower; no serious adverse effects were noted during the process.
Purpose: This study aims to evaluate current reporting practices in radiomics research, with a focus on CheckList for EvaluAtion of Radiomics research (CLEAR).
Methods: We conducted a citation search using Google Scholar to collect original research articles on radiomics citing the CLEAR guideline up to June 17, 2024. We examined the adoption of the guideline, adherence scores per publication, item-wise adherence rates, and self-reporting practices.
Association for Cardiac Research, Rome, Italy; EA 4650, Signalisation, électrophysiologie et Imagerie des Lésions d'ischémie Reperfusion Myocardique, Normandie Université, UNICAEN, 14000, Caen, France. Electronic address:
Background And Aim: During the last few years, the Seven Countries Study of Cardiovascular Diseases (SCS) produced some new analyses dealing with the relationships of a dietary score, the pool of dietary fatty acids and serum cholesterol with major types of cardiovascular disease (CVD) mortality in 10 cohorts of 6 countries made of middle-aged men followed-up for 60 years until extinction. This sparse evidence is condensed here to provide a coherent view.
Methods And Results: The Mediterranean Adequacy Index (MAI, a dietary score whose high levels depict the characteristics of the Mediterranean Diet), was highly and significantly associated in an inverse way, at country levels, with the Atherogenicity (ATI) and the Thrombogenicity (THI) indexes that included a series of dietary fatty acids.
Carriage of HLA-DQA1*05 is thought to increase the formation of anti-tumour necrosis factor alpha (TNF-α) antibodies, reducing the drug efficacy in Crohn's disease (CD) patients. However, little data are currently available for small-bowel Crohn's disease (SB-CD). A specific assessment of the impact of HLA-DQA1*05 on the clinical response to treatment with infliximab (IFX), a TNF-α antagonists, in SB-CD patients is necessary.
