AI Article Synopsis
- * Findings indicated that the width of MLC leaves didn’t significantly impact the planning target volumes (PTVs), but impacted the dose to organs at risk (OARs) more due to dose transmission differences.
- * Both test and clinical case studies revealed that while MLC type had no effect on PTVs, high-definition MLC plans provided equal or greater dose reductions to OARs compared to traditional MLCs.
Article Abstract
The aim of this study was to quantify the effect of multi-leaf collimators (MLCs) with different leaf widths on the planning of intensity-modulated radiation therapy (IMRT) and volumetric-modulated arc therapy (VMAT). Toward this objective, dose transmission through a high-definition 120-leaf MLC (HD120MLC) and 120-leaf Millennium MLC (M120MLC) was investigated, using it with a test case and clinical case studies. In test case, studies with IMRT and VMAT plans, the difference in MLC leaf width had a limited effect on planning target volumes (PTVs). Organs at risk (OARs) were more affected by a reduction in dose transmission through the MLC than by a reduction in MLC leaf width. The results of the test case studies and clinical case studies were mostly similar. In the latter, the different MLCs had no effect on the PTV regardless of the treatment method; however, the HD120MLC plans achieved dose reductions to OARs similar to or larger than the dose reduction of the M120MLC plans. The similar results of the test case and clinical case studies showed that despite a limitation of the irradiation field size, the HD120MLC plans were superior.
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| http://dx.doi.org/10.1007/s11604-017-0661-8 | DOI Listing |
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