Congenital cytomegalovirus - who, when, what-with and why to treat?

J Infect

Department of Paediatric Infectious Diseases, St Mary's Hospital, Imperial College NHS Healthcare Trust, Praed Street, London W2 1NY, UK. Electronic address:

Published: June 2017

Congenital cytomegalovirus (CMV) is the commonest cause of congenital infection worldwide and the leading non-genetic cause of sensorineural hearing loss in children. Appropriate investigations and timely decision on treatment is required as studies have shown that treatment with antiviral therapy leads to improved hearing and neurodevelopmental outcomes in the long term when started in the first month of life. This paper outlines the epidemiology, investigations in the diagnosis of congenital CMV infection and current evidence surrounding treatment.

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http://dx.doi.org/10.1016/S0163-4453(17)30197-4DOI Listing

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