A 70 year-old woman was admitted to our hospital with a 3-month history of abdominal pain, weight loss and night sweats. On physical examination, she presented with a 5 cm diameter abdominal mass extended from epigastrium to the left flank, and at least three bilateral supraclavicular adenopathies. A disseminated interdigitating dendritic cell sarcoma was diagnosed through a biopsy of the abdominal mass. After that, a CHOP regime (cyclophosphamide, doxorubicin, vincristine and prednisone) was iniciated. She died after completion of the first cycle of treatment, six months after diagnosis.
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Rev Esp Enferm Dig
December 2024
Gastroenterology, Hospital Universitario Central de Asturias, España.
A 60-year-old male was admitted for obstructive jaundice secondary to a 2 cm retroperitoneal lesion. Ultrasound endoscopy (UES) with fine needle biopsy (FNB) was performed, as well as endoscopic retrograde cholangiopancreatography (ERCP) with placement of a metal stent for bile duct drainage. Initially IgG4-related disease was suspected from FNB.
View Article and Find Full Text PDFRes Sq
November 2024
Waitt Advanced Biophotonics Center, Salk Institute for Biological Studies, La Jolla, CA, 92037.
J Hematol
October 2024
Department of Pathology, Harbor-UCLA Medical Center, Torrance, CA 90502, USA.
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) transforming into a more aggressive lymphoma (i.e., Richter syndrome) is well documented in the literature.
View Article and Find Full Text PDFTurk Patoloji Derg
August 2024
Department of Pathomorphology, Almazov National Medical Research Centre, ST. PETERSBURG, RUSSIA.
Interdigitating dendritic cell sarcoma (IDCS) is a rare and aggressive neoplasm classified within the M-group of malignant histiocytoses. Its diagnosis poses a significant challenge. This article aims to describe a rare clinical case of IDCS and to illustrate the differential diagnostic process undertaken by the authors in establishing this diagnosis.
View Article and Find Full Text PDFAm J Dermatopathol
November 2024
Department of Dermatology, Columbia University Medical Center, New York, NY.
Interdigitating dendritic cell sarcoma is a rare, aggressive hematological malignancy primarily originating in lymph nodes, with only 10 reported cases presenting in the skin (primary cutaneous interdigitating dendritic cell sarcoma). Past presentations showed erythematous nodules on the proximal extremities, back, or face. Morphologically, these neoplasms are similar to melanomas and other dendritic cell (DC) tumors, making their diagnosis difficult.
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