Introduction: Surveys state a widespread use of complementary and alternative medicine (CAM) in patients with malignant diseases. CAM methods might potentially interfere with the metabolization of tumor-specific therapy. However, there is little communication about CAM use in hematology/oncology patients between patients, CAM providers, and oncologists.
Patients And Methods: A self-administered questionnaire was handed out to all patients attending to the hematology/oncology outpatient clinic of Regensburg University Hospital. Subsequently, a chart review of all CAM users was performed.
Results: Questionnaires of 1,016 patients were analyzed. Of these patients, 30% used CAM, preferably vitamins and micronutrients. Main information sources for CAM methods were physicians/nonmedical practitioners and friends/relatives. CAM therapies were provided mainly by licensed physicians (29%), followed by nonmedical practitioners (14%) and the patients themselves (13%). Although 62% of the CAM users agreed that the oncologist may know about their CAM therapy, a chart entry about CAM use was found only in 41%.
Conclusion: CAM is frequently used by hematology/oncology patients. Systematic communication about CAM is essential to avoid possible drug interactions.
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http://dx.doi.org/10.1159/000464248 | DOI Listing |
Sci Rep
December 2024
Department of Electrical Engineering, College of Engineering, Taif University, P.O. BOX 11099, 21944, Taif, Saudi Arabia.
Weather recognition is crucial due to its significant impact on various aspects of daily life, such as weather prediction, environmental monitoring, tourism, and energy production. Several studies have already conducted research on image-based weather recognition. However, previous studies have addressed few types of weather phenomena recognition from images with insufficient accuracy.
View Article and Find Full Text PDFNat Commun
December 2024
Division of Protein & Nucleic Acid Chemistry, MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge, CB2 0QH, UK.
The rate and pattern of mutagenesis in cancer genomes is significantly influenced by DNA accessibility and active biological processes. Here we show that efficient sites of replication initiation drive and modulate specific mutational processes in cancer. Sites of replication initiation impede nucleotide excision repair in melanoma and are off-targets for activation-induced deaminase (AICDA) activity in lymphomas.
View Article and Find Full Text PDFNat Commun
December 2024
Department of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, FL, USA.
The mechanism(s) underlying gut microbial metabolite (GMM) contribution towards alcohol-mediated cardiovascular disease (CVD) is unknown. Herein we observe elevation in circulating phenylacetylglutamine (PAGln), a known CVD-associated GMM, in individuals living with alcohol use disorder. In a male murine binge-on-chronic alcohol model, we confirm gut microbial reorganization, elevation in PAGln levels, and the presence of cardiovascular pathophysiology.
View Article and Find Full Text PDFFront Big Data
December 2024
Department of Electronic and Computer Engineering (The Graduate School of Science and Engineering), Ritsumeikan University, Kusatsu, Shiga, Japan.
J Ethnopharmacol
December 2024
MecNano Technologies, Cube Incubation, Teknopark Istanbul, Istanbul 34906, Türkiye; Department of Pharmacology, Faculty of Pharmacy, Istanbul Kent University, Istanbul 34406, Türkiye; UCL Division of Surgery and Interventional Sciences, Rowland Hill Street, NW3 2PF London, UK; Art de Huile, Teknopol Istanbul, Istanbul 34930, Türkiye; Biomedical Engineering Department, University of Aveiro, Aveiro 3810-193, Portugal. Electronic address:
Ethnopharmacological Relevance: Clove is used in Indian and Chinese traditional medicine for viral diseases. Palmarosa essential oils have been traditionally used in India and Southeast Asia since ancient times and have made considerable use of them. In New Caledonia, niaouli oil is used in aromatherapy and pharmaceutical formulations to treat pain and viral diseases.
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