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Development and evaluation of a microfluidic human testicular tissue chip: a novel platform for reproductive biology and pharmacology studies.
Lab Chip
January 2025
Department of Urology, Changhai Hospital, Naval Medical University, Shanghai, China.
Organ-on-a-chip culture systems using human organ tissues provide invaluable preclinical insights into systemic functions . This study aimed to develop a novel human testicular tissue chip within a microfluidic device employing computer-aided design software and photolithography technology. Polydimethylsiloxane was used as the primary material to ensure marked gas permeability and no biotoxicity, enabling effective mimicry of the testicular microenvironment.
View Article and Find Full Text PDFA Radiograph Dataset for the Classification, Localization, and Segmentation of Primary Bone Tumors.
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January 2025
Biomedicine Discovery Institute and Department of Biochemistry and Molecular Biology, Monash University, Melbourne, VIC, 3800, Australia.
Primary malignant bone tumors are the third highest cause of cancer-related mortality among patients under the age of 20. X-ray scan is the primary tool for detecting bone tumors. However, due to the varying morphologies of bone tumors, it is challenging for radiologists to make a definitive diagnosis based on radiographs.
View Article and Find Full Text PDFInvestigating the key principles in two-step heterogeneous transfer learning for early laryngeal cancer identification.
Sci Rep
January 2025
Faculty of Applied Sciences, Macao Polytechnic University, Macao, 999078, China.
Data scarcity in medical images makes transfer learning a common approach in computer-aided diagnosis. Some disease classification tasks can rely on large homogeneous public datasets to train the transferred model, while others cannot, i.e.
View Article and Find Full Text PDFReducing reading time and assessing disease in capsule endoscopy videos: A deep learning approach.
Int J Med Inform
January 2025
University of Coimbra, Faculty of Medicine, Coimbra, Portugal; Department of Gastroenterology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal. Electronic address:
Background: The wireless capsule endoscope (CE) is a valuable diagnostic tool in gastroenterology, offering a safe and minimally invasive visualization of the gastrointestinal tract. One of the few drawbacks identified by the gastroenterology community is the time-consuming task of analyzing CE videos.
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Interventions and implementation considerations for reducing pre-treatment loss to follow-up in adults with pulmonary tuberculosis: A scoping review.
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January 2025
Faculty of Medicine and Health Sciences, Division of Epidemiology and Biostatistics, Stellenbosch University Centre for Evidence-Based Health Care, Cape Town, South Africa.
Background: Tuberculosis (TB) is a leading cause of death worldwide with over 90% of reported cases occurring in low- and middle-income countries (LMICs). Pre-treatment loss to follow-up (PTLFU) is a key contributor to TB mortality and infection transmission.
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