The representation of spatial information related to an event can influence behavior even when location is task-irrelevant, as in the case of Stimulus-Response (S-R) compatibility effects on the Simon task. However, unlike single-modality situations, which are often used to study the Simon effect, in real-life scenarios various sensory modalities provide spatial information coded in different coordinate systems. Here, we address the expression of S-R compatibility effects in mixed-modality contexts, where events can occur in 1 of various sensory modalities (i.e., vision, touch or audition). The results confirm that, in single-modality cases, Simon effects in vision are expressed in an external spatial frame of reference, while touch information is coded anatomically. Remarkably, when mixing visual and tactile trials in an unpredictable way, the Simon effect disappeared in vision whereas tactile Simon effects remained expressed in their own (anatomical) frame of reference. Mixing visual and auditory stimuli did not obliterate the visual Simon effect and S-R compatibility effects in an external reference frame were evident for both modalities. The extinction of visual Simon effects as a result of mixing visual and tactile modalities can be interpreted as a consequence of the dynamic reorganization of the weights associated to the different sources of spatial information at play. (PsycINFO Database Record
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Explor Res Clin Soc Pharm
March 2025
Division of Practice Advancement and Clinical Education, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill.
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View Article and Find Full Text PDFAtten Percept Psychophys
November 2024
Leibniz Research Center for Working Environment and Human Factors (IfADo), Dortmund, Germany.
Previous studies revealed an S-R compatibility effect between physical stimulus size and response location, with faster left (right) responses to small (large) stimuli, respectively, as compared to the reverse assignments. Here, we investigated the locus of interactions between the processing of size and spatial locations. In Experiment 1, we explored whether stimulus size and stimulus location interact at a perceptual level of processing when responses lack spatiality.
View Article and Find Full Text PDFSci Rep
November 2024
Department of Psychology, TU Dortmund University, Emil-Figge-Straße 50, 44227, Dortmund, Germany.
The spatial-size association of response codes (SSARC) effect refers to the observation that left responses are faster and more accurate to small stimuli whereas right responses are faster and more accurate to large stimuli, as compared to the reverse assignment. The underlying spatial-size associations are strongly asymmetrical with physical size/location stimuli and vocal location/size responses and allow for regular but not reciprocal SSARC effects. Recent evidence, however, points towards an important role of stimulus mode in the emergence of reciprocal compatibility effects.
View Article and Find Full Text PDFViruses
September 2024
ViiV Healthcare, 36 East Industrial Road, Branford, CT 06405, USA.
The HIV-1 maturation inhibitor (MI) VH3739937 (VH-937) inhibits cleavage between capsid and spacer peptide 1 and exhibits an oral half-life in humans compatible with once-weekly dosing. Here, the antiviral properties of VH-937 are described. VH-937 exhibited potent antiviral activity against all HIV-1 laboratory strains, clinical isolates, and recombinant viruses examined, with half-maximal effective concentration (EC) values ≤ 5.
View Article and Find Full Text PDFAlgorithmica
September 2024
Department of Computer Science, Bar-Ilan University, Ramat Gan, Israel.
The Set Packing problem is, given a collection of sets over a ground set , to find a maximum collection of sets that are pairwise disjoint. The problem is among the most fundamental NP-hard optimization problems that have been studied extensively in various computational regimes. The focus of this work is on parameterized complexity, Parameterized Set Packing (PSP): Given parameter , is there a collection such that the sets in are pairwise disjoint? Unfortunately, the problem is not fixed parameter tractable unless , and, in fact, an "enumerative" running time of is required unless the exponential time hypothesis (ETH) fails.
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