Study of adverse drug reactions in patients with diabetes attending a tertiary care hospital in New Delhi, India.

Indian J Med Res

Department of Medicine/Preventive Cardiology, Hamdard Institute of Medical Sciences & Research, Associated Hakeem Abdul Hameed Centenary Hospital, Jamia Hamdard, New Delhi, India.

Published: February 2017

The present prospective observational study was carried out in a tertiary care hospital in New Delhi, India from May 2014 to June 2015 to report adverse drug reactions (ADRs) in patients with type 2 diabetes mellitus (T2DM) using antidiabetic drugs. A total of 220 patients (121 males, 99 females) were enrolled. ADRs were recorded on the prescribed form. Causality and severity assessment was done using Naranjo's probability scale and modified Hartwig and Siegel's severity scale, respectively. Commonly prescribed drugs were biguanides, peptide hormone and sulphonylurea. A total of 26 ADRs were recorded (16 in males and 10 in females). Most commonly observed ADRs were related to endocrine and gastrointestinal system. Severity assessment of ADRs showed seven (26.9%) ADRs as moderate, and 19 (73.1%) as mild. No severe reactions were observed. ADRs were mostly related to endocrine and gastrointestinal system. More information on prescribed drugs and their side effects is required for ensuring patient safety.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501058PMC
http://dx.doi.org/10.4103/ijmr.IJMR_109_16DOI Listing

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