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In Vitro Evaluation of the Fresenius Kabi CATSmart Autotransfusion System. | LitMetric

AI Article Synopsis

  • - The study evaluates the performance of the CATSmart Continuous Autotransfusion System compared to the C.A.T.S system in collecting and processing shed blood during surgeries, focusing on volume differences (200, 700, and 1,000 mL).
  • - Results showed that both systems effectively concentrated and washed blood, with similar mean hematocrit (HCT) levels post-processing (59.63% for CATSmart and 57.71% for C.A.T.S), and very close red blood cell recovery rates (85.41% vs. 84.99%).
  • - The findings confirm that CATSmart is non-inferior to the C.A.T.S system in producing high-quality blood products, effectively eliminating

Article Abstract

Use of autotransfusion systems to collect, wash, and concentrate shed blood during surgical procedures is a widely used method for reducing postoperative anemia and the need for blood transfusions. The aim of this study was to evaluate the CATSmart Continuous Autotransfusion System wash program performance with small (200 or 700 mL) and large volumes (1,000 mL) of shed blood and to determine non-inferiority of the CATSmart to the C.A.T.S system. Human whole blood was collected in citrate phosphate dextrose, diluted, and divided into two aliquots to be processed as a pair using the C.A.T.S and CATSmart systems with their corresponding wash programs: low-volume, high quality/smart, or emergency wash. Final packed red cell product was analyzed for red blood cell (RBC), white blood cell, and platelet counts; hemoglobin; hemolysis; RBC recovery rates; and elimination of albumin, total protein, and potassium. The mean hematocrit (HCT) after processing with CATSmart and C.A.T.S systems were 59.63% and 57.71%, respectively. The calculated overall RBC recovery rates on the CATSmart and C.A.T.S systems were 85.41% and 84.99%, respectively. Elimination of albumin (97.5%, 98.0%), total proteins (97.1%, 97.5%), and potassium (92.1%, 91.9%) were also calculated for the CATSmart and C.A.T.S systems. The CATSmart and C.A.T.S systems both provided a high-quality product in terms of HCT, protein elimination, and hemolysis rates across the range of tested shed blood volumes and all wash programs. The study was able to confirm the CATSmart is non-inferior to the C.A.T.S system.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474889PMC

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