The Northern Ohio Trauma System (NOTS), consisting of multiple hospital systems, was established in 2010 to improve trauma outcomes. This study assessed its impact on mortality and time to definitive care, focusing especially on the severely injured patients. NOTS trauma registry was queried for all trauma activations from 2008 to 2013. The years between 2008-2009 and 2011-2013 were designated as pre- and post-NOTS, respectively. Data from 2010 was excluded as a transitional year. Two trauma centers (TCs) closed in 2010. Predetermined patient subgroups were analyzed. A total of 27,843 patients were examined. Mean age was 46 and 64 per cent were male. Median Injury Severity Score (ISS) was five, and 87 per cent sustained blunt injuries. Of these, 10,641 patients were pre-NOTS and 17,202 were post-NOTS. Comparing the two groups, mortality decreased from 5 to 4 per cent post-NOTS (P < 0.001); median time to definitive care increased by 12 minutes post-NOTS. Multivariate logistic regression showed that NOTS implementation was an independent predictor for survival (P = 0.008), whereas time to definitive care was not. Subgroup analyses demonstrated mortality reductions post-NOTS for all subgroups except patients with penetrating injuries, where mortality remained the same despite an increase in ISS. Patients with ISS ≥15 had a 23 per cent relative reduction in mortality, and their median time to definitive care decreased by 12 minutes. Implementation of a collaborative, regional trauma system was associated with mortality reduction and shortened time to definitive care in the severely injured patients. These findings highlight the importance of collaboration in the future development of regional trauma systems.
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Parasitol Res
December 2024
Department of Parasitology, Faculty of Veterinary Medicine, Ondokuz Mayıs University, Samsun, Turkey.
The superfamily Ascaridoidea are parasitic nematodes in vertebrates, including birds and humans. In order to investigate the presence and distribution of these parasitic nematodes in birds acting as the definitive host, 157 birds of 64 bird species belonging to 16 orders were collected and necropsied in the Kızılırmak Delta area in the Bafra district of Samsun province. The parasites collected were fixed in 70% ethyl alcohol and identified under a light microscope, and morphologically important regions were photographed for identification.
View Article and Find Full Text PDFRespir Res
December 2024
Department of Medicine and Surgery, Pediatric Clinic, University of Parma, Via Gramsci 14, 43126, Parma, Italy.
Background: Exercise-induced bronchoconstriction (EIB) is common in children with asthma but can be present also in children without asthma, especially athletes. Differential diagnosis includes several conditions such as exercise-induced laryngeal obstruction (EILO), cardiac disease, or physical deconditioning. Detailed medical history, clinical examination and specific tests are mandatory to exclude alternative diagnoses.
View Article and Find Full Text PDFBMC Cardiovasc Disord
December 2024
School of Psychology, University of Southampton, Southampton, UK.
Background: Blood pressure (BP) control following stroke is important but currently sub-optimal. This trial aimed to determine whether self-monitoring of hypertension with telemonitoring and a treatment escalation protocol, results in lower BP than usual care in people with previous stroke or transient ischaemic attack (TIA).
Methods: Unblinded randomised controlled trial, comparing a BP telemonitoring-based intervention with control (usual care) for hypertension management in 12 primary care practices in England.
BMC Cardiovasc Disord
December 2024
Department of Cardiovascular Medicine, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, People's Republic of China.
Backgrounds: Due to the high mortality and hospitalization rate in chronic heart failure (HF), it is of great significance to study myocardial nutrition conditions. Amino acids (AAs) are essential nutrient metabolites for cell development and survival. This study aims to investigate the associations and prognostic value of plasma branched-chain amino acid/aromatic amino acid ratio (Fischer's ratio, FR) in patients with left ventricular ejection fraction (LVEF) ≤ 50%.
View Article and Find Full Text PDFJ Prosthet Dent
December 2024
Clinical Professor and Program Director, University of Connecticut Health Center, Farmington, Conn.; and Private practice, Glastonbury, Conn. Electronic address:
An important step in the workflow for a complete arch fixed implant-supported prosthesis is the fabrication of a prototype resin prosthesis to allow the patient to visualize the definitive treatment outcome and also to use as an interim prosthesis. Producing a prototype prosthesis with the natural appearance of the gingival color and contour has been challenging. Current methods include painted stains, manually applied pink composite resin or autopolymerizing acrylic resin, and multicolored resin blocks, but these are all relatively expensive, have less than optimal esthetics, and are labor-intensive and time-consuming.
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