Background: Transarterial embolization of liver hemangiomas has not been considered to be consistently effective.
Methods: The charts of 25 patients who underwent superselective transarterial chemoembolization with the bleomycin-lipiodol emulsion were evaluated retrospectively.
Results: Twenty-two patients had abdominal pain; asymptomatic/vaguely symptomatic enlargement was the treatment indication in three patients. A single session was conducted in 17 patients, two sessions in 7 and three sessions in one. After the first session, lesion volume decreased by median (range) 51% (10-92%) from median (range) 634 (226-8435) to 372(28-4710) cm (p < 0.01), after a median period of 4 months (range 2-8). A second session was performed in eight patients (median (range) initial volume 1276 (441-8435) cm) with persistent complaints and/or large lesions receiving feeders from both right and left hepatic arteries (staged treatment). Median (range) lesion size decreased further from 806 (245-4710) to 464 (159-2150) cm (p < 0.01). Three patients experienced a postembolization syndrome that persisted after the first week. Seventeen of the 22 symptomatic patients (77%) reported resolution or marked amelioration of complaints. Regrowth after initial regression was not observed during median (range) 14 (8-39) months of follow-up (n:18).
Conclusion: Transarterial chemoembolization with the bleomycin-lipiodol emulsion is a potential alternative to surgery for symptomatic/enlarging liver hemangiomas. Volume reduction is universal, and symptom control is satisfactory. Centrally located and very large (>1000 cm) lesions may require two sessions.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00268-017-4069-5 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Temporary Flow Diversion in Oncological Embolization Procedures Using Degradable Starch Microspheres.
Diagnostics (Basel)
December 2024
Vascular and Interventional Radiology Department, Cardarelli Hospital, Via A. Cardarelli 9, 80131 Naples, Italy.
Objectives: This study aims to report on the application of degradable starch microspheres to provide flow diversion by means of temporary embolization of healthy tissues in oncological endovascular procedures when tumor feeding vessels are not selectively accessible.
Methods: This is a multicenter retrospective analysis of patients undergoing visceral embolization procedures of malignancies. The inclusion criteria were as follows: flow diversion performed by injection of degradable starch microspheres, visceral embolization procedures with unfeasible superselective catheterism of the target, and a malignant pathology.
Effectiveness of super-selective digital subtraction angiography and 3D rotational digital subtraction venography for a developmental venous anomaly with an arteriovenous malformation: A case report and literature review.
Surg Neurol Int
November 2024
Department of Neurosurgery, Hamamatsu University School of Medicine, Hamamatsu, Japan.
Background: Arteriovenous malformation (AVM) and developmental venous anomaly (DVA) rarely coexist. Developing a surgical strategy to treat this co-occurrence is difficult due to the unclear pathogenesis. We report the use of super-selective digital subtraction angiography (DSA) and Three-dimensional (3D) rotational digital subtraction venography (DSV) to develop a surgical strategy for complex AVM draining into a DVA.
View Article and Find Full Text PDFComplete contrast staining of hepatocellular carcinoma during drug-eluting bead chemoembolization predicts a favorable response.
J Clin Imaging Sci
November 2024
Department of Radiology and Medical Imaging, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Article Synopsis
- - The study aimed to see if complete contrast staining (CCS) of hepatocellular carcinoma (HCC) during the first session of drug-eluting bead transarterial chemoembolization (DEBTACE) can predict treatment response.
- - Researchers analyzed data from 41 patients with solitary HCC, categorizing them into CCS and non-CCS groups based on their contrast staining observed via 2D fluoroscopy during their initial treatment session.
- - Results showed that CCS was present in over half of the patients and was linked to significantly higher rates of complete response in subsequent treatment sessions compared to those without CCS.
Liver Ischemia After Transarterial Embolization for Hepatic Trauma Injury.
Diagnostics (Basel)
November 2024
Department of Radiology, Wan Fang Hospital, Taipei Medical University, Taipei 116, Taiwan.
Transarterial embolization (TAE) is a routine procedure performed by interventional radiologists to manage traumatic hepatic injuries. Hepatic super-selective TAE rarely results in ischemia within the embolized area. In this case, the initial CT scan revealed significant contrast extravasation, leading to an urgent TAE.
View Article and Find Full Text PDFAtypical venous drainage system and distinct vascular characteristics in pediatric intracerebral hemorrhage caused by multiple micro arteriovenous malformations.
Childs Nerv Syst
December 2024
Department of Neurosurgery, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Shimotsugagun, Tochigi, 321-0293, Japan.
Article Synopsis
- Hemorrhagic brain micro-AVMs are common in pediatric cases but usually have low bleeding rates, even in conditions like hereditary hemorrhagic telangiectasia that involve multiple malformations.
- A 10-year-old girl with multiple hemorrhagic micro-AVMs required emergency surgery due to hematoma; intraoperative findings revealed complex vascular structures and atypical bleeding sources.
- Superselective angiography proved essential for identifying micro-AVMs and informing treatment, while also highlighting the need for caution due to the potential impacts of invasive procedures on vascular sensitivity and visibility.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!