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http://dx.doi.org/10.1177/1178221817704692 | DOI Listing |
Alzheimers Dement
December 2024
University of Calgary, Calgary, AB, Canada.
Background: The overuse of antipsychotics in persons with dementia in long-term care (LTC) has been a source of clinical concern, public attention, and policy intervention for over 30 years. Targeted quality improvement, broader awareness of risks, and other initiatives have resulted in substantial reductions in antipsychotic use in LTC settings in North America and elsewhere. Limited evidence suggests that reductions in antipsychotic use may be resulting in unintended consequences, such as substitution with alternate, but similarly harmful, psychotropic medications.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of São Paulo Medical School, São Paulo, Brazil.
Introduction: Patients with severe cognitive impairment, with the progression of the disease, show behavioral impairments, loss of functionality and, in many cases, swallowing changes (dysphagia). Dysphagia comes with serious complications that can cause health damage, such as malnutrition, dehydration and serious lung damage secondary to aspirations. Eating process goes beyond nutritional intake, as it has a social, cultural, behavioral, physical and cognitive component.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Alzheimer Center Amsterdam, Neurology, Vrije Universiteit Amsterdam, Amsterdam UMC location VUmc, Amsterdam, Netherlands.
Background: Data-driven criteria for DNA testing were implemented in routine care of Alzheimer Center Amsterdam. We aimed to explore patients' perspectives and considerations regarding their decision to (not) be tested for a monogenic cause of their disease.
Methods: In this mixed method study, 150 of 519 new patients visiting Alzheimer Center Amsterdam who fulfilled the criteria were offered DNA-diagnostics: 86(57%) accepted, 64(43%) did not.
Med J Islam Repub Iran
September 2024
Department of Surgery with course of anesthesiology and resuscitation, Kazakhstan-Russian Medical University, Almaty, Kazakhstan.
Background: Brain ischemia is one of the leading causes of morbidity and mortality in infants. Currently, many factors influence the degree of development of ischemia and the consequences affecting the child's body. The purpose of this study was to find the characteristics of the physical and psychomotor development of children with brain ischemia.
View Article and Find Full Text PDFPhilos Trans R Soc Lond B Biol Sci
January 2025
Centre for Biodiversity and Environment Research, Department of Genetics, Evolution and Environment,, University College London, London WC1E 6BT, UK.
Zoonotic and vector-borne infectious diseases are among the most direct human health consequences of biodiversity change. The COVID-19 pandemic increased health policymakers' attention on the links between ecological degradation and disease, and sparked discussions around nature-based interventions to mitigate zoonotic emergence and epidemics. Yet, although disease ecology provides an increasingly granular knowledge of wildlife disease in changing ecosystems, we still have a poor understanding of the net consequences for human disease.
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