Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.4103/0377-4929.208401 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Human parietal epithelial cells as Trojan horses in albumin overload.
Sci Rep
January 2025
Kidney Histomorphology and Molecular Biology Laboratory, Nephrology Unit, Department of Medicine - DIMED, University of Padua, Via Giustiniani 2, 35128, Padua, Italy.
Parietal Epithelial Cells (PECs) activation and proliferation are common to several distinct forms of glomerulopathies. Due to several stimuli, PECs can change to a progenitor (CD24 and CD133/2) or a pro-sclerotic (CD44) phenotype. In addition, PECs, which are constantly exposed to filtered albumin, are known to be involved in albumin internalization, but how this mechanism occurs is unknown.
View Article and Find Full Text PDFC3 glomerulopathy in children: experience at a resource-limited center.
Clin Exp Pediatr
November 2024
Department of Paediatric Nephrology, St Johns Medical College Hospital, Bangalore, India.
Background: In children, C3 glomerulopathy (C3G) is a heterogeneous disease characterized by diverse clinicopathological profiles and kidney outcomes. However, diagnostic work-up in resource-limited settings is challenging because of the unavailability of complement assays and limited access to electron microscopy or genetic testing.
Purpose: This study aimed to describe the clinicopathological features and response to immunosuppression and evaluate renal outcomes among children with C3G in a resource-limited setting.
Is the Prevalence of Biopsy-Proven Glomerulopathies in Adults Changing Over Time?
Maedica (Bucur)
September 2024
"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Article Synopsis
- A study in Romania reviewed 1,254 adults with biopsy-proven glomerulopathies (GP) from 2008 to 2017 to assess changes in frequency and causes for kidney biopsies (KB).
- The research found that while nephrotic syndrome was a common reason for KB, its occurrence decreased significantly over the decade, with older patients showing more advanced kidney damage and chronic kidney function decline.
- Additionally, there was a notable increase in cases of diabetic nephropathy and crescentic glomerulonephritis, suggesting changes in diagnostic practices rather than an actual rise in GP prevalence among older adults.
Complete renal response of IgA vasculitis with steroid and mycophenolate mofetil in an adult HIV patient.
Trop Doct
October 2024
Senior Resident, Department of Nephrology, All India Institute of Medical Sciences, Raipur, India.
IgA vasculitis in adult HIV patients is rare and not well understood. Data on treatment of IgA vasculitis associated with HIV is sparse and limited to case reports. Highly active antiretroviral therapy (HAART) is the mainstay therapy for inducing remission.
View Article and Find Full Text PDFHow Stem and Progenitor Cells Can Affect Renal Diseases.
Cells
August 2024
Department of Precision and Regenerative Medicine and Ionian Area, University of Bari Aldo Moro, 70124 Bari, Italy.
Article Synopsis
- * Recent research focuses on how these cells interact with the kidney structure and respond to damage, offering potential for new treatment methods.
- * The review discusses the role of these cells in both healing mechanisms and the development of various kidney disorders, suggesting they can either worsen or improve conditions depending on the context.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!