AI Article Synopsis

  • Isolates of serotype 3 linked to invasive pneumococcal disease were collected from 124 cases across Japan from April 2010 to March 2013.
  • A penicillin-resistant strain (KK0981) from an adult patient was found among these isolates.
  • Whole-genome analysis revealed that KK0981 is a recombinant strain, combining traits from both penicillin-resistant and penicillin-susceptible serotype 3 strains.

Article Abstract

isolates of serotype 3 were collected from cases of invasive pneumococcal disease ( = 124) throughout Japan between April 2010 and March 2013. A penicillin-resistant (PRSP) isolate from an adult patient, strain KK0981 of serotype 3, was identified among these strains. Whole-genome analysis characterized this PRSP as a recombinant strain derived from PRSP of serotype 23F with the locus (20.3 kb) replaced by that of a penicillin-susceptible strain of serotype 3.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571339PMC
http://dx.doi.org/10.1128/AAC.00478-17DOI Listing

Publication Analysis

Top Keywords

serotype
5
genome evolution
4
evolution penicillin
4
penicillin resistance
4
resistance serotype
4
serotype streptococcus
4
streptococcus pneumoniae
4
pneumoniae capsular
4
capsular switching
4
switching isolates
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!