isolates of serotype 3 were collected from cases of invasive pneumococcal disease ( = 124) throughout Japan between April 2010 and March 2013. A penicillin-resistant (PRSP) isolate from an adult patient, strain KK0981 of serotype 3, was identified among these strains. Whole-genome analysis characterized this PRSP as a recombinant strain derived from PRSP of serotype 23F with the locus (20.3 kb) replaced by that of a penicillin-susceptible strain of serotype 3.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5571339 | PMC |
http://dx.doi.org/10.1128/AAC.00478-17 | DOI Listing |
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