Mitochondrial DNA depletion induces innate immune dysfunction rescued by IFN-γ.

John D Widdrington Aurora Gomez-Duran Jannetta S Steyn Angela Pyle Marie-Helene Ruchaud-Sparagano Jonathan Scott Simon V Baudouin Anthony J Rostron John Simpson Patrick F Chinnery

J Allergy Clin Immunol

Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Medical Research Council Mitochondrial Biology Unit, Cambridge Biomedical Campus, Cambridge, United Kingdom; Department of Clinical Neurosciences, University of Cambridge, Cambridge, United Kingdom. Electronic address:

Published: November 2017

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5667580	PMC
http://dx.doi.org/10.1016/j.jaci.2017.04.048	DOI Listing

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