Pseudomonas aeruginosa is a major pathogen responsible for nosocomial infections. A 16-year retrospective report from 2000 to 2015 was conducted to assess the antimicrobial resistance of P. aeruginosa in Southern China. A total of 1387 P. aeruginosa were collected from inpatients and outpatients. Susceptibility testing results were interpreted according to the Clinical and Laboratory Standards Institute (CLSI, 2015). Piperacillin, piperacillin-tazobactam, ceftazidime, aminoglycosides and carbapenems remained to be active against P. aeruginosa, with resistance rates ranging from 5.6% to 29.7%. Generally, ampicillin, ampicillin-sulbactam, ceftriaxone and trimethoprim-sulfamethoxazole nearly lost the effect on P. aeruginosa, as the resistance rates increase up to 90%. Notably, sputum and blood specimen showed higher resistance rates than other sources in carbapenems, suggesting more caution should be paid on the choice of antibiotic against infections associated with respiratory tract.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.micpath.2017.06.018 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
HIV-1 Antiretroviral Drug Resistance in Mozambique: A Systematic Review and Meta-Analysis.
Viruses
November 2024
Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, Universidade de Lisboa, Avenida Professor Gama Pinto, 1649-003 Lisbon, Portugal.
This systematic review assessed the prevalence of transmitted and acquired HIV drug resistance (HIVDR) and the associated risk factors in Mozambique. A search of the PubMed, Cochrane, B-On, and Scopus databases up to December 2023 was conducted and included 11 studies with 1118 HIV-1 pol sequences. Drug resistance mutations (DRMs) to NNRTIs were found in 13% of the drug-naive individuals and 31% of those on ART, while NRTI resistance occurred in 5% and 10%, respectively.
View Article and Find Full Text PDFChallenges of Multidrug-Resistant Tuberculosis Meningitis: Current Treatments and the Role of Glutathione as an Adjunct Therapy.
Vaccines (Basel)
December 2024
College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA 91766-1854, USA.
Multidrug-resistant tuberculosis (MDR-TB) poses a significant global health threat, especially when it involves the central nervous system (CNS). Tuberculous meningitis (TBM), a severe manifestation of TB, is linked to high mortality rates and long-term neurological complications, further exacerbated by drug resistance and immune evasion mechanisms employed by Mycobacterium tuberculosis (Mtb). Although pulmonary TB remains the primary focus of research, MDR-TBM introduces unique challenges in diagnosis, treatment, and patient outcomes.
View Article and Find Full Text PDFCOVID-19 Testing Behavior as a Predictor of COVID-19 Vaccination in Southeastern Louisiana: A Longitudinal Cohort Study.
Vaccines (Basel)
November 2024
Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD 21205, USA.
Global COVID-19 vaccination effort faces the challenges of vaccine hesitancy and resistance, rooted in misinformation and institutional distrust. Addressing these barriers with customized messaging is essential, yet the relationship between vaccine hesitancy and other health-seeking behaviors, like COVID-19 testing, has been underexplored. This study assessed COVID-19 vaccine uptake in Southeastern Louisiana across 10 pharmacies and clinics in areas with historically high rates of COVID-19 infection.
View Article and Find Full Text PDFImproving the Impact Resistance and Post-Impact Tensile Fatigue Damage Tolerance of Carbon Fiber Reinforced Epoxy Composites by Embedding the Carbon Nanoparticles in Matrix.
Polymers (Basel)
December 2024
Department of Mechanical and Mechatronic Engineering, National Taiwan Ocean University, Keelung 202301, Taiwan.
The effect of dispersing multiwalled carbon nanotubes (MWCNTs) and graphene nanoplatelets (GNPs) in the matrix on the low-velocity impact resistance and post-impact residual tensile strength of the carbon fiber reinforced epoxy composite laminates has been experimentally analyzed in this study. The composite specimens with the matrix reinforced by different nanoparticle types and various nanoparticle concentrations (0.1, 0.
View Article and Find Full Text PDFXylem Hydraulics of Two Temperate Tree Species with Contrasting Growth Rates.
Plants (Basel)
December 2024
CAS Key Laboratory of Forest Ecology and Management, Institute of Applied Ecology, Chinese Academy of Sciences, Shenyang 110016, China.
Hydraulic functionality is crucial for tree productivity and stress tolerance. According to the theory of the fast-slow economics spectrum, the adaptive strategies of different tree species diverge along a spectrum defined by coordination and trade-offs of a suite of functional traits. The fast- and slow-growing species are expected to differ in hydraulic efficiency and safety; however, there is still a lack of investigation on the mechanistic association between tree growth rate and tree hydraulic functionality.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!