This corrects the article DOI: 10.1038/nplants.2017.18.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1038/nplants.2017.103 | DOI Listing |
Nucleic Acids Res
December 2024
State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai 200237, China.
Treatment of (Mab) infections is very challenging due to its intrinsic resistance to most available drugs. Therefore, it is crucial to discover novel anti-Mab drugs. In this study, we explored an intrinsic resistance mechanism through which Mab resists echinomycin (ECH).
View Article and Find Full Text PDFSynth Syst Biotechnol
August 2024
Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, PR China.
is a significant industrial microorganism. Traditional gene editing techniques relying on homologous recombination often exhibit low efficiency due to their reliance on resistance genes. Additionally, the established CRISPR gene editing technology, utilizing Cas9 endonuclease, faces challenges in achieving simultaneous knockout of multiple genes.
View Article and Find Full Text PDFFront Microbiol
July 2024
Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Cyanobacteria have great potential in CO-based bio-manufacturing and synthetic biological studies. The filamentous cyanobacterium, sp. strain BL0902, is comparable to () in commercial-scale cultivation while proving to be more genetically tractable.
View Article and Find Full Text PDFMol Genet Genomics
August 2024
Stem Cells and Biotherapy Engineering Research Center of Henan, National Joint Engineering Laboratory of Stem Cells and Biotherapy, School of Life Science and Technology, Xinxiang Medical University, Number 601, Jinsui Road, Xinxiang, 453003, Henan, China.
The clustered regularly interspaced short palindromic repeats (CRISPR) and their associated protein (Cas) system is a gene editing technology guided by RNA endonuclease. The CRISPR-Cas12a (also known as CRISPR-Cpf1) system is extensively utilized in genome editing research due to its accuracy and high efficiency. In this paper, we primarily focus on the application of CRISPR-Cpf1 technology in the construction of disease models and gene therapy.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!