The congenital granular-cell epulis is an uncommon pedunculated tumor of the alveolar mucosa found only in newborn infants. This lesion can present an alarming appearance and interfere with efforts at nursing. The generally accepted treatment is excision through the pedicle, and recurrence is not to be anticipated. An example of a tumor fulfilling the clinical and histopathologic criteria of this lesion is reported.
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From prenatal diagnosis to surgical treatment: two case reports of congenital granular cell epulis.
Pathol Oncol Res
July 2024
Department of Oral and Maxillofacial Surgery, Qi Lu Hospital of Shandong University, Jinan, Shandong, China.
Article Synopsis
- This study discusses a coordinated approach to treating two infants born with congenital granular cell epulis (CGCE), identified through ultrasound during pregnancy.* -
- A team of specialists, including surgeons and pediatricians, collaborated to create a treatment plan, leading to successful removal of the oral masses after cesarean delivery.* -
- Immunohistochemical analysis of the removed lesions provided key insights, highlighting the significance of early prenatal diagnosis for managing this rare condition.*
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Department of Oral and Maxillofacial Surgery, Qingdao Women and Children's Hospital, Qingdao, Shandong, China.
Congenital granular cell epulis (CGCE) is a rare disease, particularly when it affects multiple oral and maxillofacial regions. We present the case of a female neonate with 4 asymptomatic masses attached to the maxillary and mandibular gingiva as well as the tongue. Due to the size of the masses causing feeding and respiratory difficulties, lesion removal was performed under general anesthesia.
View Article and Find Full Text PDFCongenital Granular Cell Tumour - Case Report and Review of Literature.
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Rationale: Congenital orofacial swellings in neonates are mainly limited to vascular malformations and neuroectodermal benign tumours. Congenital granular cell tumour (CGCT) is a rare condition affecting neonates with a prevalence rate of 6 in 1 million. Our report provides a brief review of diagnosis and management.
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