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Background: HIV self-testing (HIVST) can improve HIV testing uptake by offering convenience and privacy. Yet HIVST accessibility and uptake remain limited in Lake Victorias beach communities where HIVST holds promise to address many barriers highly mobile populations of men in fishing communities face. We assessed HIVST knowledge and acceptability among highly mobile fishermen, a high priority population for HIV prevention and treatment, participating in a social network-based study ("Owete"; NCT04772469) to promote HIV testing, prevention, and treatment in Kenya.
View Article and Find Full Text PDFHunting the Cell Cycle .
Life (Basel)
September 2024
Laboratory of Bacterial Communication and Anti-Infection Strategies, EA 4312, University of Rouen, 76000 Rouen, France.
Article Synopsis
- The author examines the bacterial cell cycle, updating mechanisms that regulate it, including factors like calcium dynamics and membrane structures, informed by physical and chemical principles.
- Key questions explored include the reasons behind DNA replication processes, the structure of DNA, and the concepts of cell division and metabolic balance.
- The text also suggests new experimental methods for testing theories related to the bacterial cell cycle, along with innovative ideas about DNA packing and virtual bacterial computation.
Natural Feed Supplements From Crustacean Processing Side Streams for Improved Growth of Finfishes and Crustaceans: A Review.
J Anim Physiol Anim Nutr (Berl)
October 2024
Department of Food Science and Technology, Pondicherry University, Puducherry, India.
Article Synopsis
- - Natural feed additives from plant, animal, and microbial sources are being explored in aquaculture to enhance feed quality, reduce chemical use, ensure food safety, and support sustainability, addressing global food security challenges.
- - Shellfish processing side streams, particularly from crustaceans like shrimp, contain valuable nutrients (proteins, lipids, chitin) that can be transformed into natural feed supplements, promoting better growth in fish and shellfish while adhering to organic and antibiotic-free farming practices.
- - The review emphasizes the potential of crustacean by-products (like shrimp head meal and chitosan derivatives) as effective aquafeed additives, which can lessen environmental impacts from waste, decrease reliance on traditional fish meal, and enhance the economic viability
Disease models of Leigh syndrome: From yeast to organoids.
J Inherit Metab Dis
November 2024
NeuroCure Cluster of Excellence, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Article Synopsis
- Leigh syndrome (LS) is a severe mitochondrial disease caused by mutations in over 100 genes that impair cellular respiration and mainly affect brain function, leading to cognitive and motor issues.
- Various model systems, including yeast, fruit flies, zebrafish, and mice, have been developed over 30 years to study the disease's mechanisms and symptoms.
- Recent advancements in using induced pluripotent stem cells (iPSCs) enable researchers to examine LS mutations in human cells, facilitating high-throughput drug screening and the potential for personalized treatments.
Shortening the early diagnostic window of Hg-induced liver injury with a HO-activated fluorescence/afterglow imaging assay.
J Hazard Mater
December 2024
State Key Laboratory of Southwestern Chinese Medicine Resources, School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 611137, China; Sichuan New Green Pharmaceutical Technology Development Co. Ltd., Chengdu 611930, China. Electronic address:
Article Synopsis
- * A novel fluorescence/afterglow probe called FA-HO has been developed for precise detection of hydrogen peroxide in cells, zebrafish, and mice affected by mercury-induced oxidative stress.
- * FA-HO's afterglow emission allows for better monitoring of hydrogen peroxide with less interference, enabling earlier and non-invasive detection of mercury-induced liver injury.
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