Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473234PMC
http://dx.doi.org/10.1074/jbc.A116.771097DOI Listing

Publication Analysis

Top Keywords

quantitative mapping
4
mapping microtubule-associated
4
microtubule-associated protein
4
protein map2c
4
map2c phosphorylation
4
phosphorylation regulatory
4
regulatory protein
4
protein 14-3-3ζ-binding
4
14-3-3ζ-binding sites
4
sites reveals
4

Similar Publications

Small Molecular Oligopeptides Adorned with Tryptophan Residues as Potent Antitumor Agents: Design, Synthesis, Bioactivity Assay, Computational Prediction, and Experimental Validation.

J Chem Inf Model

January 2025

Key Laboratory for Photonic and Electronic Bandgap Materials, Ministry of Education, College of Chemistry and Chemical Engineering, Harbin Normal University, Harbin 150025, China.

Tryptophan participates in important life activities and is involved in various metabolic processes. The indole and aromatic binuclear ring structure in tryptophan can engage in diverse interactions, including π-π, π-alkyl, hydrogen bonding, cation-π, and CH-π interactions with other side chains and protein targets. These interactions offer extensive opportunities for drug development.

View Article and Find Full Text PDF

Purpose: To provide a fast quantitative imaging approach for a 0.55T scanner, where signal-to-noise ratio is limited by the field strength and k-space sampling speed is limited by a lower specification gradient system.

Methods: We adapted the three-dimensional spiral projection imaging MR fingerprinting approach to 0.

View Article and Find Full Text PDF

Leaf is the main photosynthetic organ at the seedling stage of rapeseed and leaf size is a crucial agronomic trait affecting rapeseed yield. Understanding the genetic mechanisms underlying leaf size is therefore important for rapeseed breeding. In this study, QTL mapping for three traits related to leaf size, i.

View Article and Find Full Text PDF

Functional characterization of eQTLs and asthma risk loci with scATAC-seq across immune cell types and contexts.

Am J Hum Genet

January 2025

Center for Molecular Medicine and Genetics, Wayne State University, Detroit, MI, USA; Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI 48201, USA. Electronic address:

cis-regulatory elements (CREs) control gene transcription dynamics across cell types and in response to the environment. In asthma, multiple immune cell types play an important role in the inflammatory process. Genetic variants in CREs can also affect gene expression response dynamics and contribute to asthma risk.

View Article and Find Full Text PDF

Background: Hydroxychloroquine and Chloroquine (CQ) and Hydroxychloroquine (HCQ) are antimalarial drugs with well-known anti-inflammatory and antiviral effects used to treat various diseases, with few side effects. After COVID-19 emergence, numerous researches from around the world have examined the potential of using CQ or HCQ as potential treatment of COVID-19. However, conflicting outcomes have been found in COVID-19 clinical trials after treatment with CQ or HCQ.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!