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Tools for regulating metabolic diseases: extracellular vesicles from adipose macrophages.
Front Endocrinol (Lausanne)
December 2024
Department of Rehabilitation, Jiujiang College Hospital, Jiujiang, Jiangxi, China.
Metabolic diseases have gradually become one of the most significant global medical burdens. Diseases such as obesity, diabetes, and metabolic syndrome, along with their complications, are clinically categorized as metabolic diseases. Long-term oral medication significantly reduces patient compliance and quality of life.
View Article and Find Full Text PDFUnderstanding frailty: a qualitative study of older heart failure patients' frail experience and perceptions of healthcare professionals with frailty.
BMC Geriatr
December 2024
Nursing Department, The Second Affiliated Hospital, Jiangxi Medical College, Nan Chang University, Min de Road #, Nan Chang, Jiang Xi, 330006, People's Republic of China.
Background: Although frailty is highly prevalent in hospitalized older heart failure (HF) patients, its management is often delayed. Understanding the unique experiences of frail elderly HF patients and the perceptions of healthcare professionals (HPs) regarding frailty can facilitate the integration of frailty prevention and intervention into clinical practice. This study aimed to use a descriptive qualitative approach to obtain the experiences of frailty in older HF patients and the perceptions of HPs concerning frailty.
View Article and Find Full Text PDFExploring alternative approaches to next of kin consenting in the semi-emergency neurosurgical scenario.
Med J Malaysia
November 2024
Universiti Malaya, Faculty of Medicine, Department of Surgery, Division of Neurosurgery, Kuala Lumpur, Malaysia.
Introduction: Prior to any surgical intervention, obtaining informed consent is necessary. In situations where patients are unable to provide informed consent due to mental incapacity or reduced consciousness, the responsibility falls on surrogate decision-makers, typically family members. This predicament commonly arises during neurosurgical emergencies.
View Article and Find Full Text PDFSegmental Absence of Intestinal Musculature: An Enticing Predicament.
J Assoc Physicians India
November 2024
Assistant Professor, Department of Pathology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Maharishi Markandeshwar (Deemed to be University), Ambala, Haryana, India.
Segmental absence of intestinal musculature (SAIM) was first identified as a cause of intestinal perforation and remains difficult to diagnose clinically. Diagnosing SAIM preoperatively can be difficult; however, detection during the surgical procedure may be feasible if gross observations reveal bowel alterations such as a thinned-out wall, signs of gangrenous changes, or adjacent bowel dilatation. A final diagnosis can be made with the help of histopathology, making it a gold standard.
View Article and Find Full Text PDFThe urgent need for clear and concise regulations on exosome-based interventions.
Stem Cell Reports
November 2024
MLIP Law Office, Minato-ku, Tokyo 105-0004, Japan.
Turner and colleagues recently argued that countries with unclear laws and regulations regarding stem cells, exosomes, and other regenerative medicine products should develop and enforce more comprehensive regulatory structures. We fully agree with this opinion and discuss that failure to do so may lead to troubling predicaments, such as the Japanese cases, where patients are at risk of serious complications or even death.
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