New research describes regulatory pathways for reticulated thrombocytosis in a mouse model of diabetes.
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Antimicrobial Effects of Thonningianin a (TA)-Loaded Chitosan Nanoparticles Encapsulated by a PF-127 hydrogel in Diabetic Wound Healing.
Int J Nanomedicine
December 2024
Department of Ophthalmology, the Affiliated Hospital of Southwest Medical University, Luzhou, 646000, People's Republic of China.
Background And Purpose: Diabetic wounds are serious chronic complications of diabetes and can lead to amputation and death. Although considerable progress has been made in drugs and materials for treating it, it's still an urgent clinical problem as the materials and drugs have potential therapeutic drawbacks, such as low delivery efficiency and poor tissue permeability. To promote diabetic wound healing, a composite of thonningianin A (TA)-loaded chitosan nanoparticles (CNPS) encapsulated by a Pluronic F-127 (PF-127) hydrogel (TA-CNPS-PF) was developed in this study.
View Article and Find Full Text PDFIt's reticulated: the liver at the heart of atherosclerosis.
J Endocrinol
July 2018
Division of ImmunometabolismBaker Heart and Diabetes Institute, Melbourne, Australia.
Platelets play a critical role in both the initiation and progression of atherosclerosis, and even more so in the ensuing atherothrombotic complications. Low-dose aspirin remains the mainstay of antiplatelet therapy in high-risk patients by reducing the risk of myocardial ischemia, stroke or death due to cardiovascular disease. However, antiplatelet therapies lose their efficacy in people with diabetes mellitus, increasing the risk of future atherothrombotic events.
View Article and Find Full Text PDFIt's reticulated: Diabetes, atherosclerosis, and reticulated platelets.
Sci Transl Med
June 2017
Division of Infectious Diseases, Center for Global Health, Weill Medical College of Cornell University, New York, NY 10065, USA. Email:
New research describes regulatory pathways for reticulated thrombocytosis in a mouse model of diabetes.
View Article and Find Full Text PDFConjunctival swab cytology from a guinea pig: it's elementary!
Vet Clin Pathol
June 2005
Department of Veterinary Physiological Sciences and the Zoological Medicine Service, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
Three 3-month-old guinea pigs (Cavia porcellus) were evaluated for purulent ocular discharge. Conjunctival swabs were obtained for cytologic evaluation of Wright's-Giemsa-stained preparations. The specimen from the most severely affected guinea pig consisted primarily of karyolytic neutrophils and small lymphocytes.
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