Background: An outbreak of measles was reported in Timor-Leste during 2011. A concerted response at national level utilized this opportunity to improve measles immunization coverage rates.
Methods: Health Management Information System and Surveillance System data were utilized to describe the outbreak. Attack rates and case fatality rates (CFR) were calculated using standard methods. Evaluation surveys were used to access immunization coverage. Proceedings of weekly meetings of the National Committee for Control of Disease Outbreaks were reviewed.
Results: A total of 739 cases and 8 deaths were reported to the Surveillance Unit. Most (>82%) of the measles cases were reported from Dili and Ermera districts. The attack rate was 1.3 per 1000 population and CFR was 1.1%. The response was coordinated by the National Committee for Control of Disease Outbreaks, which included case management, active and passive surveillance, communication and measles immunization among six-month to 14-year old children. Immunization activity targeted 495 000 children, i.e. almost one-half of the Timor-Leste population and achieved high coverage (85%).
Conclusions: The outbreak highlighted gaps in the immunity against measles. The National Committee for Control of Disease Outbreaks ensured a coordinated response which led to prevention of deaths from measles due to early case management with vitamin A supplementation, and high measles immunization coverage.
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http://dx.doi.org/10.4103/2224-3151.206919 | DOI Listing |
China CDC Wkly
December 2024
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases (NITFID), National Immunization Programme, Chinese Center for Disease Control and Prevention, Beijing, China.
Background: Since rubella was incorporated into the national disease surveillance system in 2004, rubella incidence has changed dramatically. This study analyzed the impact of immunization strategies on the age-specific and sex-specific incidence of rubella in China from 2004 to 2023 to inform efforts to accelerate rubella elimination.
Methods: Annual rubella-containing vaccine (RCV) coverage levels, reported rubella cases and incidence, and vaccination status of cases were obtained from the National Immunization Program Information Management System, the National Notifiable Diseases Reporting System, and the Measles Surveillance System, and used to describe temporal trends.
Dev Biol
December 2024
Department of Biology and Neuroscience Program, Hamline University. Electronic address:
Connecting socially relevant topics with biological content can boost student engagement and comprehension. Autism Spectrum Disorder (ASD) is an increasingly prevalent diagnosis with a number of intersecting topic areas between developmental biology and social justice. Here I describe two exercises that I developed to engage students in learning opportunities that link scientific process learning goals with real-world applications.
View Article and Find Full Text PDFVaccine
December 2024
Scientific Advisor and Emeritus Director, National Influenza Centre, Valladolid, 47010, Spain.
Histopathology
December 2024
University of Virginia Health System, Charlottesville, VA, USA.
The resurgence of measles, syphilis, and HIV presents a significant threat to global health, especially in the wake of the COVID-19 pandemic. These three infections involve lymph nodes and have unique pathologic findings in lymph nodes. We explore the pathological and clinical characteristics of these infections, focusing on their involvement of lymph nodes and their pathologic diagnosis in lymph node specimens.
View Article and Find Full Text PDFJ Med Virol
December 2024
Department of Medical Biotechnologies, University of Siena, Siena, Italy.
Despite the availability of a highly efficacious vaccine, a global resurgence of measles infections has occurred, largely due to decreased vaccination coverage and waning immunity following the two-dose vaccination schedule. This study aims to assess the cellular immune response in individuals who did not respond to the two-dose MMR vaccine and evaluate the efficacy and durability of immune responses after booster doses. An observational study was conducted involving 24 individuals who were seronegative for measles years after completing the two-dose MMR vaccine schedule.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!