AI Article Synopsis
- This study aimed to assess the effectiveness of the micro swim-up method for sperm preparation in ICSI treatments, comparing it to a traditional centrifuge method.
- In a multicentric study with 140 ICSI cycles, two groups were formed based on the sperm preparation techniques used: one used discontinuous gradients and the other used the micro swim-up method.
- Results showed no significant difference in fertilization rates, but the micro swim-up group had higher blastulation and pregnancy rates, suggesting it may be a cost-effective and efficient alternative to traditional methods.
Article Abstract
Objective: The aim of this study was to evaluate the efficacy of a non-expensive, easy and fast technique (direct micro swim-up) for sperm preparation in intracytoplasmic sperm injection (ICSI) treatments without the use of centrifuge.
Methods: We carried out a multicentric study in which a total of 140 ICSI-cycles were included. Sibling oocytes were divided into two groups according to semen preparation procedures: group A, discontinuous gradients (DG) (oocytes n=668), and group B, direct micro swim-up (MSU) (oocytes n=660). We analyzed differences in some key performance indicators.
Results: Fertilization rates were not statistically different between the DG and MSU groups (76.0% vs. 81.8%, respectively, p=0.248); while significant differences were found in blastulation rates per fertilized oocytes (41.7% vs. 58.5%, p=0.009), blastulation rates per D3 embryos (46.1% vs. 63.7%, p=0.045), and pregnancy rates (25.8% vs. 41.9%, p=0.045). The abortion rate was reduced in the MSU group as compared to DG, but not in a significant manner (12.9% vs. 29.4%, p=0.161).
Conclusion: The MSU procedure has the advantage of reducing costs, time and mismatches, while ensuring comparable, and in some cases, better results than DG treatments. This technique can therefore be used as an alternative method to other conventional semen treatments.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5473700 | PMC |
| http://dx.doi.org/10.5935/1518-0557.20170022 | DOI Listing |
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