Through cooperative actions of iridium catalyst and NaOTf additive we report a new direct access to nitrogen bi-heteroarenes via hydrogen-evolution cross-coupling of the β-site of indoles/pyrrole with the α-site of N-heteroarenes. The reaction proceeds in an atom- and redox-economic fashion together with the merits of an easily available catalyst system, broad substrate scope, excellent functional tolerance, and no need for external oxidants, offering a practical way to create π-conjugated systems.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/acs.orglett.7b01349 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A comparison of the accuracy and feasibility of a low-cost mobile application versus higher-cost handheld 3D scanner for digital ear prosthetics.
ANZ J Surg
December 2024
Royal Prince Alfred Institute of Academic Surgery, Sydney Local Health District, Sydney, New South Wales, Australia.
Background: Facial prosthetics are an important means to rehabilitate patients with congenital or acquired facial defects. However, with a time-consuming manual workflow and workforce shortage, access to facial prosthetics is limited in Australia and worldwide, especially for rural and remote patients. Optical 3D scanning has been increasingly integrated in digitizing data.
View Article and Find Full Text PDFEngaging older adults in the process of aging research: a multimethod study evaluating the experience and efficacy of a citizen advisory group for a dementia risk reduction program.
Res Involv Engagem
December 2024
Rotman Research Institute, Baycrest Academy for Research and Education, 3560 Bathurst Street, Toronto, ON, M6A 2E1, Canada.
Background: Collaborative research with end-users is an effective way to generate meaningful research applications and support greater impact on practice and knowledge exchange. To address these needs, a Citizen Advisory Group (CAG) of nine older adults (ages 64-80, 67% women) was formed to advise scientists on the development of Brain Health PRO (BHPro), a web-based platform designed to increase dementia prevention literacy and awareness. The current study evaluated if the CAG met its objectives, how inclusion of the CAG aligned with collaborative research approaches, and the CAG's experience and satisfaction throughout the development process.
View Article and Find Full Text PDFImplications of optic disc rotation in the visual field progression of myopic open-angle glaucoma.
Graefes Arch Clin Exp Ophthalmol
December 2024
Department of Ophthalmology, Cathay General Hospital, 280, Section 4, Ren-Ai Rd, Taipei, Taiwan, 106.
Purpose: To investigate the relationship between the characteristics of optic disc rotation and visual field (VF) progression in patients with myopic open-angle glaucoma (OAG).
Methods: We included 53 eyes from 53 myopic OAG patients who were followed-up over a 3-year period. The characteristics of optic disc rotation including the degree of optic disc rotation, direction of optic disc rotation, and optic disc rotation-VF defect correspondence were investigated.
Towards a more objective and high-throughput spheroid invasion assay quantification method.
Sci Rep
December 2024
Department of Biomedical Engineering, Worcester Polytechnic Institute, Worcester, MA, 01605, USA.
Multicellular spheroids embedded in 3D hydrogels are prominent in vitro models for 3D cell invasion. Yet, quantification methods for spheroid cell invasion that are high-throughput, objective and accessible are still lacking. Variations in spheroid sizes and the shapes of the cells within render it difficult to objectively assess invasion extent.
View Article and Find Full Text PDFMediating and moderating factors between stigma and adaptability to return to work for cancer survivors.
Sci Rep
December 2024
School of Nursing and Rehabilitation, Nantong University, Nantong, 226001, Jiangsu, China.
Adaptability to return to work is a process by which cancer survivors(CSs) utilize accessible resources to reconstruct themselves. While the stigma, financial situation and social support are known to influence their adaptability to return to work, the mechanisms by which these factors work remain unclear. This study proposes a moderated mediation model to signify a pathway linking stigma to the adaptability to return to work.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!