Adaptive lifespan development involves individuals' simultaneous coordination of motivational engagement across multiple domains of life. The present study tests this proposition using data from the Midlife in the United States National Longitudinal Study of Health and Well-Being (MIDUS I and II). Results from multilevel model analyses indicate that participants' engagement with, perceived control over, and reported quality in the domains of work, health, and family relationships follow general trajectories across adulthood that reflect age-graded and socially structured opportunities. Participants' engagement with each domain of life was associated with more positive reports of life quality and perceived control within these domains. These positive engagement benefits were least prominent in strongly age-graded domains (i.e., health), and most pronounced in less age-graded domains (i.e., work and family relationships). Results further indicate that individuals adaptively managed their engagement across these central domains of adulthood, in that cross-domain associations were positive or at least non-detrimental. While cross-domain engagement benefits were present across all four domains, they were most prominent in naturally facilitative pairings (e.g., relationships with one's spouse/partner and children). Overall, the results provide support for the proposition of the motivational theory of life-span development that adaptive lifespan development involves individual's active, simultaneous, and synchronous engagement with central domains of life.
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http://dx.doi.org/10.1080/15427609.2016.1234308 | DOI Listing |
J Nanobiotechnology
January 2025
Department of Orthopedic Surgery, Fujian Medical University Union Hospital, Fuzhou, 350001, China.
Overproduction of reactive oxygen species (ROS), elevated synovial inflammation, synovial hyperplasia and fibrosis are the main characteristic of microenvironment in rheumatoid arthritis (RA). Macrophages and fibroblast-like synoviocytes (FLSs) play crucial roles in the progression of RA. Hence, synergistic combination of ROS scavenging, macrophage polarization from pro-inflammatory M1 phenotype towards M2 anti-inflammatory phenotype, and restoring homeostasis of FLSs will provide a promising therapeutic strategy for RA.
View Article and Find Full Text PDFCell Commun Signal
January 2025
Laboratory of Veterinary Clinical Pharmacology, College of Veterinary Medicine, Inner Mongolia Agricultural University, No. 306, Zhaowuda Road, Hohhot, 010018, China.
Wound healing is a highly coordinated process driven by intricate molecular signaling and dynamic interactions between diverse cell types. Nod-like receptor pyrin domain-containing protein 3 (NLRP3) has been implicated in the regulation of inflammation and tissue repair; however, its specific role in skin wound healing remains unclear. This study highlights the pivotal role of NLRP3 in effective skin wound healing, as demonstrated by delayed wound closure and altered cellular and molecular responses in NLRP3-deficient (NLRP3) mice.
View Article and Find Full Text PDFPlant Methods
January 2025
Faculty of Agriculture, Agriculture and Forestry University, Bharatpur, 13712, Nepal.
Background: Crossover interactions stemming from phenotypic plasticity complicate selection decisions when evaluating hybrid maize with superior grain yield and consistent performance. Consequently, a two-year, region-wide investigation of 45 hybrids maize across Nepal was performed with the aim of disclosing both site and wide adapted hybrids. Utilizing an innovative "ProbBreed" package, based on Bayesian probability analysis of randomized complete block designs with three replicated trials at each station, this study substantively streamlines hybrids maize selection.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Sport Games, Józef Piłsudski University of Physical Education in Warsaw, Marymoncka 34, Warsaw, 00-968, Poland.
This study aimed to examine and compare the anthropometric profiles, motor skills, game-related abilities, and functional capacities of under-15 (U-15) and under-16 (U-16) male basketball players, evaluate the impact of maturity offset, and predict performance across physical and sport-specific domains. A total of 234 athletes participated in a comprehensive test battery, assessing morphological (height, mass, standing reach), physical (sprinting, agility, jump height, endurance), technical (jump shot, free throws, dribbling), and functional movement screen variables. The U-16 group outperformed U-15 players in physical characteristics and jump height.
View Article and Find Full Text PDFSci Data
January 2025
Shanghai Artificial Intelligence Research Institute Co., Ltd., Shanghai, 200240, China.
Academic data processing is crucial in scientometrics and bibliometrics, such as research trending analysis and citation recommendation. Existing datasets in this domain have predominantly concentrated on textual data, overlooking the importance of visual elements. To bridge this gap, we introduce a multidisciplinary multimodal aligned dataset (MMAD) specifically designed for academic data processing.
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