Chemical composition and antifungal activity of Hedera helix leaf ethanolic extract.

Acta Biol Hung

Department of Biology, Faculty of Biology and Geology, "Babeş-Bolyai" University, 42 Republicii Street, 400015 Cluj-Napoca , Romania.

Published: June 2017

AI Article Synopsis

  • A 50% ethanol extract from Hedera helix leaves was analyzed for its content of polyphenols and sterols, revealing the presence of compounds like rutin, quercetin, kaempferol, and stigmasterol.
  • The antifungal properties of this extract were tested against various phytopathogenic fungi, with an observed minimum inhibitory concentration (MIC) ranging from 10-14%, which was comparable to the synthetic antifungal fluconazole.
  • This study marks the first assessment of the antifungal effects of ivy leaf extract on these specific fungal species, and suggests its potential use for managing plant diseases and possibly human health issues.

Article Abstract

The 50% ethanol extract obtained from Hedera helix leaves was investigated regarding the presence and quantity of polyphenols, sterols and in vitro antifungal activity against phytopathogenic fungi. The chemical analysis revealed the presence of rutin, quercetin and kaempferol in the non-hydrolysed sample and quercetin and kaempferol in the hydrolysed sample and stigmasterol in the ivy leaf extract (nonhydrolysed sample). The antifungal activity against phytopathogenic fungi (Aspergillus niger, Botrytis cinerea, B. tulipae, Fusarium oxysporum f. sp. tulipae, Penicillium gladioli, and Sclerotinia sclerotiorum) was assessed using an agar dilution assay. The results are expressed as the minimum inhibitory concentration (MIC = 10-14%) and were compared to a synthetic antifungal drug - fluconazole (MIC = 8-30%). This report presents the first screening of the antifungal activity of the ivy leaf extract on these plant pathogenic fungi species, aiming to use the ivy leaf extract for controlling different diseases of vegetables and ornamental plants, in addition to human disorders.

Download full-text PDF

Source
http://dx.doi.org/10.1556/018.68.2017.2.7DOI Listing

Publication Analysis

Top Keywords

antifungal activity
16
ivy leaf
12
leaf extract
12
hedera helix
8
activity phytopathogenic
8
phytopathogenic fungi
8
quercetin kaempferol
8
antifungal
5
extract
5
chemical composition
4

Similar Publications

Lactams Exhibit Potent Antifungal Activity Against Monospecies and Multispecies Interkingdom Biofilms on a Novel Hydrogel Skin Model.

APMIS

January 2025

Oral Sciences Research Group, Glasgow Dental School, School of Medicine, Dentistry and Nursing, College of Medical, Veterinary and Life Sciences, Glasgow, UK.

Infections of intact and damaged skin barriers and keratin are frequently associated with complex biofilm communities containing bacteria and fungi, yet there are limited options for successful management. This study intended to focus on the utility of some novel proprietary lactam molecules, quorum sensing (QS)-derived halogenated furanones, which act to block the QS pathway, against key fungal pathogens of the skin (Candida albicans, Malassezia furfur and Microsporum gypseum). Moreover, we aimed to assess how these actives performed against complex interkingdom biofilms in a clinically relevant model.

View Article and Find Full Text PDF

An 83-year-old male with a history of radial keratotomy and laser-assisted in situ keratomileusis (LASIK) presented with symptoms of a non-resolving corneal ulcer in the right eye that had been present for five months. The patient was treated with antibacterial, antiviral, and antifungal medications over that period, with multiple recurrences that prompted referral to our tertiary center for management. Following a 48-hour cessation of all medications, a corneal biopsy was performed which grew .

View Article and Find Full Text PDF

spp. rarely cause infection in humans and are most common in the immunocompromised population. Pulmonary nocardiosis is the most common presentation.

View Article and Find Full Text PDF

Cellobiose lipids (CBLs) are a class of glycolipid biosurfactants produced by various fungal strains. These compounds have gained significant interest due to their surface-active and antifungal properties, which are comparable to traditional synthetic surfactants and antimicrobials. Despite their potential applicability in various cosmetic, pharmaceutical, and agricultural formulations, significantly less research has been focused on their production and purification in comparison to other glycolipid biosurfactants, such as mannosylerythritol lipids (MELs) and sophorolipids.

View Article and Find Full Text PDF

The synthesis of nanomaterials from PGPB is an exciting approach and it's often used in agriculture as nano-fertilizers and nano-pesticides. The present study reports a new approach to biosynthesis of silver nanoparticles (AgNP), using bacterial metabolites as agents to reduce Ag, which will remain as coating agents able to prevent microbial growth. Silver NP were biosynthesized using the bacterial metabolites produced by the beneficial strain Pseudomonas sp.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!