Objective: We present the use of targeted temperature management in a tertiary-level intensive care unit, in three patients who experienced an out-of-hospital cardiac arrest.
Case Report: Three young patients experienced an out-of-hospital non-coronary cardiac arrest. The causes of the cardiac arrest were: Wolf-Parkinson-White syndrome, drug overdose and long-QT syndrome. All patients were resuscitated according to the advanced cardiac life support guidelines, and treated with targeted temperature management, with a target temperature of 33°C for 24 hours. After completion of targeted temperature management, all the patients regained full consciousness and were discharged from hospital without any neurological sequelae.
Conclusion: Targeted temperature management may improve survival and neurological outcome in patients after out-of-hospital cardiac arrest.
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http://dx.doi.org/10.5644/ama2006-124.186 | DOI Listing |
Dialogues Health
June 2025
Department of Public Health Science, Indian Institute of Public Health Gandhinagar (IIPHG), Gujarat, India.
Climate change presents a significant global public health challenge for animals and humans. Due to geography, climate, population, and urbanization, India is vulnerable to extreme heat. This review aims to explore the impact of heat on human and animal health in India.
View Article and Find Full Text PDFTo facilitate the development of compact multi-wavelengths lasers, we reported the experimental demonstration of dual seed sources master oscillator power amplifier (MOPA) QCLs. The devices were based on a sandwich configuration consisting of dual seed sources and a central power amplifier. Emission spectrum of devices was modulated by switching seed sources.
View Article and Find Full Text PDFThis paper proposes a multispectral temperature measurement method integrating multiple information sources to address inaccuracies in target temperature measurements in multispectral thermometry when emissivity is unknown. This algorithm leverages convolutional neural networks for image recognition to convert one-dimensional voltage data into two-dimensional voltage spectral images. To enhance accuracy, it combines emissivity trend inversion with emissivity constraint algorithms.
View Article and Find Full Text PDFOne Health Outlook
January 2025
Medical Virology Unit, Faculty of Basic Medical and Applied Sciences, Lead City University and Primary Health Care Board, Ibadan, Oyo State, Nigeria.
Background: Dengue fever (DF) poses a growing global threat, necessitating a comprehensive one-health approach to address its complex interplay between human, animal, and environmental factors. In Oyo State, Nigeria, the true burden of DF remains unknown due to underdiagnosis and misdiagnosis as malaria, exacerbated by poor health-seeking behavior, weak surveillance systems, and inadequate health infrastructure. Adopting a one-health approach is crucial to understanding the dynamics of DF transmission.
View Article and Find Full Text PDFJ Control Release
January 2025
Key Laboratory of Drug-Targeting and Drug Delivery System of the Education Ministry and Sichuan Province, Sichuan Engineering Laboratory for Plant-Sourced Drug and Sichuan Research Center for Drug Precision Industrial Technology, West China School of Pharmacy, Sichuan University, Chengdu 610041, China. Electronic address:
Adeno-associated viruses (AAV) have significant potential as vaccine carriers due to their excellent biosafety and efficient antigen gene delivery. However, most AAV vaccines show limited capacity to transduce antigen-presenting cells (APCs) following intramuscular injection which may cause inadequate cellular immune responses and undesired side effects due to transducing other tissues or cells. Herein, we developed a soluble microneedle patch for targeting the AAV vaccines to the epidermal and dermal APCs.
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