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Anti-PL-7, anti-Ro/SSA, anti-Mi-2, and anti-TIF1-γ correlate with specific patterns of histopathologic features in dermatomyositis: An analysis of 39 skin biopsy specimens from 25 patients.
J Cutan Pathol
April 2024
Dartmouth Geisel School of Medicine, Hanover, New Hampshire, USA.
Background: In dermatomyositis (DM), myositis-specific and myositis-associated antibodies have been correlated with clinical features. It is unknown if histopathologic findings in lesional skin biopsies correlate with serologic subtypes of DM.
Methods: A retrospective chart review of patients with DM was performed.
Frequency of Autoantibodies on Non-Hodgkin Lymphoma.
Healthcare (Basel)
August 2023
Unidad de Investigación Epidemiológica y en Servicios de Salud, CMNO OOAD, Jalisco, Instituto Mexicano del Seguro Social, Guadalajara 44340, Mexico.
(1) Background: Non-Hodgkin Lymphoma is a neoplasm that can significantly compromise the immune system, but timely assessment can change the patient outcome. In cancer, the activation of the immune system could lead to the secretion of autoantibodies. (2) Methods: A retrospective cohort study was performed from 2017 to 2019 in patients with Non-Hodgkin Lymphoma diagnosed with a biopsy.
View Article and Find Full Text PDFRheumatoid factor is associated with severe COVID-19.
Int J Rheum Dis
May 2023
Division of Rheumatology, Department of Internal Medicine, Soonchunhyang University Hospital, Bucheon, South Korea.
Aim: Coronavirus disease 2019 (COVID-19) has been proposed as triggering autoimmunity. The aim of this study was to evaluate the presence and clinical significance of autoantibodies in patients with COVID-19.
Methods: We retrospectively collected data from 245 patients who were hospitalized for COVID-19.
Feasibility of Indirect immunofluorescence (IIF) alone as a screening method for antinuclear antibody in connective diseases in India's sub-Himalayan region.
Indian J Pathol Microbiol
November 2022
Department of Microbiology, AIIMS, Rishikesh, Uttarakhand; Department of Microbiology, F.A.A. Medical College, Barpeta, Assam, India.
Background: For the management of connective tissue disorders (CTDs), antinuclear antibody (ANA) testing is essential, both from diagnostic and prognostic points of view. Usually, patterns obtained by ANA-IIF testing correlates to specific autoantibodies as obtained from the test for ENA (by LIA/ELISA, etc.).
View Article and Find Full Text PDFTargets of autoantibodies in acquired hemophilia A are not restricted to factor VIII: data from the GTH-AH 01/2010 study.
Blood Adv
January 2023
Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.
The root cause of autoantibody formation against factor VIII (FVIII) in acquired hemophilia A (AHA) remains unclear. We aimed to assess whether AHA is exclusively associated with autoantibodies toward FVIII or whether patients also produce increased levels of autoantibodies against other targets. A case-control study was performed enrolling patients with AHA and age-matched controls.
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