Legume Lectins: Proteins with Diverse Applications.

Int J Mol Sci

Coordinacion de Ciencia de los Alimentos, Centro de Investigacion en Alimentacion y Desarrollo, A.C., Apartado Postal 1735, Hermosillo, Sonora 83304, Mexico.

Published: June 2017

Lectins are a diverse class of proteins distributed extensively in nature. Among these proteins; legume lectins display a variety of interesting features including antimicrobial; insecticidal and antitumor activities. Because lectins recognize and bind to specific glycoconjugates present on the surface of cells and intracellular structures; they can serve as potential target molecules for developing practical applications in the fields of food; agriculture; health and pharmaceutical research. This review presents the current knowledge of the main structural characteristics of legume lectins and the relationship of structure to the exhibited specificities; provides an overview of their particular antimicrobial; insecticidal and antitumor biological activities and describes possible applications based on the pattern of recognized glyco-targets.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5486065PMC
http://dx.doi.org/10.3390/ijms18061242DOI Listing

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