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A rarity in breast pathology: A male case of Rosai-Dorfman disease and literature review. | LitMetric

Rosai-Dorfman Disease (RDD) is a rare disease that normally presents with bilateral cervical lymph node enlargement. Systemic symptoms of fever and weight loss may be present but patients are usually asymptomatic. This benign disease tends to regress on its own without treatment but there have been cases that required treatment with steroids or chemotherapeutic regimes. Extranodal disease in the breast is extremely rare, with only three cases identified in the male breast. The patient in this study presented with an asymptomatic right breast lump identified incidentally. After excisional biopsy, a diagnosis of RDD was confirmed on immunochemistry and histopathology.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466548PMC
http://dx.doi.org/10.1016/j.ijscr.2017.05.011DOI Listing

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