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Validity of the Berlin questionnaire in detecting obstructive sleep apnea: A systematic review and meta-analysis. | LitMetric

AI Article Synopsis

  • The study reviewed the effectiveness of the Berlin questionnaire for screening obstructive sleep apnea (OSA) by analyzing data from various medical databases.
  • Results showed that its diagnostic utility varied significantly based on the population studied, definitions of hypopnea, and metrics used for diagnosis, revealing good sensitivity and specificity in sleep clinic populations.
  • The authors recommend more consistent definitions and further research in diverse populations to better understand the questionnaire's utility as a clinical and epidemiological screening tool for OSA.

Article Abstract

We aimed to systematically review the Berlin questionnaire as a screening tool for obstructive sleep apnea. We systematically searched PubMed, Embase, and Scopus databases, reviewed articles reporting the Berlin questionnaire's diagnostic utility as measured against type-1 polysomnography, and performed meta-analyses where possible. Thirty five eligible articles showed that the Berlin questionnaire's diagnostic utility varied by study population, definition of hypopnea used, and apnea-hypopnea index threshold used. It had good sensitivity and specificity for detecting clinically relevant obstructive sleep apnea as well as any obstructive sleep apnea in the sleep clinic population. Despite limited evidence, it showed modest to high sensitivity for detecting clinically relevant obstructive sleep apnea or any obstructive sleep apnea in other clinical and general population subgroups. Its specificity was relatively low. Possible reasons for variability in reported diagnostic utility of the Berlin questionnaire are multifaceted. We conclude that the Berlin questionnaire is useful as a clinical screening test and epidemiological tool in the sleep clinic population. Despite limited evidence, it likely has potential clinical and research utility in other populations. Adopting more consistent methodological definitions and focussing more on the general population and specific clinical populations to determine its usefulness as a clinical or epidemiological screening tool are recommended.

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Source
http://dx.doi.org/10.1016/j.smrv.2017.04.001DOI Listing

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