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The adaptation of the GameSquad exergaming intervention for young adults with Down syndrome: A pilot feasibility study.
Disabil Health J
December 2024
Division of Physical Activity and Weight Management, Department of Internal Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS, 66160, USA. Electronic address:
Background: Exergames may be a feasible alternative to in-person exercise that is adaptable for adults with Down Syndrome (DS).
Objective: The purpose of this study was to conduct a 12-week pilot trial to assess the feasibility of exergames for adults with DS.
Methods: Adults with DS were provided Ring Fit Adventure™ which uses a resistance ring and body weight to perform cardiovascular and strength exercises.
Improved Glycemic Control during a One-Week Adventure Camp in Adolescents with Type 1 Diabetes-The DIACAMP Study.
Biosensors (Basel)
September 2024
Division of Endocrinology and Diabetology, Medical University of Graz, 8036 Graz, Austria.
Adolescence remains a crucial age associated with diabetes distress in individuals living with type 1 diabetes (T1D). The Austrian organization "Diabär" regularly hosts a one-week adventure camp for adolescents (12-18 years) living with T1D. The camp focuses on "fun activities" without a structured educational protocol in order to minimize diabetes distress and increase diabetes management skills.
View Article and Find Full Text PDFNovel 3-substituted coumarins inspire a custom pharmacology prediction pipeline: an anticancer discovery adventure.
Future Med Chem
October 2024
Department of Organic & Medicinal Chemistry, Faculty of Pharmacy, University of Sadat City, 32897, Egypt.
This research aims to expand the established pharmacological space of tumor-associated carbonic anhydrases (TACAs) by exploring the synthetically accessible chemical space of 3-substituted coumarins, with the help of pharmacology prediction. 52 novel 3-substituted coumarins were sketched, prioritizing synthetic feasibility. Their pharmacological potentials were estimated using a custom machine-learning approach.
View Article and Find Full Text PDFImpact of Fruit and Vegetable Enzyme Supplementation on Aerobic Performance and Lactate Response in Older Adults Following High-Intensity Interval Exercise Through Exergaming: Randomized Experimental Matched-Pair Study.
JMIR Serious Games
June 2024
Physical Education Office, National Taipei University of Business, Taipei, Taiwan.
Background: Exercise offers substantial health benefits but can induce oxidative stress and inflammation, especially in high-intensity formats such as high-intensity interval exercise (HIIE). Exergaming has become an effective, enjoyable fitness tool for all ages, particularly older adults. Enzyme supplements may enhance exercise performance by improving lactate metabolism and reducing oxidative stress.
View Article and Find Full Text PDFValidation of a natural language processing algorithm using national reporting data to improve identification of anesthesia-related ADVerse evENTs: The "ADVENTURE" study.
Anaesth Crit Care Pain Med
August 2024
Department of Anesthesiology and Critical Care Medicine, Lapeyronie University Hospital, 34295 Montpellier Cedex 5, France; Inserm Unit 1298 Montpellier NeuroSciences Institute, Montpellier University, 34295 Montpellier Cedex 5, France.
Background: Reporting and analysis of adverse events (AE) is associated with improved health system learning, quality outcomes, and patient safety. Manual text analysis is time-consuming, costly, and prone to human errors. We aimed to demonstrate the feasibility of novel machine learning and natural language processing (NLP) approaches for early predictions of adverse events and provide input to direct quality improvement and patient safety initiatives.
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