The ongoing debate concerning the existence of malignant transformation of branchial cleft cysts has been analyzed, with the aid of previous reports and reviews in the literature. Six new cases are presented and illustrated. These occurred in 4 male and 2 female patients, having an average age of 60 years. Two of the lesions were within the parotid salivary gland. The longest period of survival was 3 1/2 years. New criteria for the acceptability of tumors as primary branchiogenic cancers are proposed. We believe that, using these strict criteria, rare examples of primary branchiogenic carcinomas do exist; their treatment should include whide local excision, followed by ipsilateral radical neck dissection.
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http://dx.doi.org/10.1016/s0301-0503(79)80009-0 | DOI Listing |
J Stomatol Oral Maxillofac Surg
September 2024
Department of Oral and Maxillofacial Surgery, First Affiliated Hospital of Naval Medical University, No. 168 Changhai Road, Yangpu District, Shanghai 200433 China. Electronic address:
Zhonghua Zhong Liu Za Zhi
June 2024
Department of Radiation Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.
Hua Xi Kou Qiang Yi Xue Za Zhi
April 2023
State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases & Dept. of Oral Pathology, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China.
Malignant transformation arising in benign lymphoepithelial cysts is a complex and rare occurrence, and related research is limited. This study presents a case of the malignant degeneration of lymphoepithelial cyst in parapharyngeal space. Clinicopathological features and differential diagnosis are discussed with literature review to provide reference for clinical diagnosis and treatment management.
View Article and Find Full Text PDFOrv Hetil
March 2023
1 Pécsi Tudományegyetem, Általános Orvostudományi Kar, Klinikai Központ, Fül-Orr-Gégészeti és Fej-Nyaksebészeti Klinika Pécs, Munkácsy M. u. 2., 7621 Magyarország.
Branchial cleft cyst is the most common birth defect involving the neck. Malignant transformation is known, however, differentiating from a neck metastasis of a squamous cell carcinoma of unknown primary is challenging. Even though there are strict criterias, the diagnosis of this entity remains controversial.
View Article and Find Full Text PDFRom J Morphol Embryol
January 2023
Department of ENT, Bucharest Emergency University Hospital, Bucharest, Romania; Department of ENT, University of Medicine and Pharmacy of Craiova, Romania;
Congenital branchial fistulas and cysts are an interesting subject in cervical pathology. There are congenital malformations with late expression in young adults that require correct diagnosis and appropriate treatment. We review essential notions of cervical embryology to understand the mechanism of occurrence of these malformations and their clinical expression.
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