AI Article Synopsis
- This study evaluates how left ventricular wall function changes after a heart attack (STEMI) and seeks to identify if measuring specific layers of the heart can predict heart remodeling.
- Researchers followed 39 STEMI patients who underwent treatment and compared their heart function to 30 healthy individuals using echocardiograms at two points: shortly after treatment and six months later.
- Results indicated that while there was improvement in heart function over time, the patients still showed lower strain measurements compared to healthy controls, and epicardial strain was identified as a significant predictor for heart remodeling issues following the heart attack.
Article Abstract
Objectives: To evaluate left ventricular wall function after ST segment elevation myocardial infarction(STEMI) by layer-specific analysis and determine if the layer-specific parameters can predict left ventricular remodeling(LVR).
Methods: Thirty nine patients with first STEMI who had successful primary percutaneous coronary intervention(P-PCI) were studied, while 30 healthy individuals were included as normal control. Echocardiographic examinations were performed in STEMI patients within 48 h after P-PCI (before follow-up) and 6 months later (follow-up). Three dimensional cardiac function and longitudinal, circumferential 3-layer strain were analyzed.
Results: In STEMI, longitudinal endocardial strain was higher than epicardial strain (<0.01), circumferential strain decreased from endocardium to epicardium gradually (<0.01). Longitudinal and circumferential 3-layer strain at follow-up was higher than that before follow-up (<0.01), but lower than that in control group( <0.05). LVR group had lower longitudinal and circumferential 3-layer strain (<0.05). Longitudinal epicardial strain was the independent predictor of LVR(odds ratio:3.332,95% confidence interval:1.124-3.882,=0.03), the cut off value of -9% yielded 89.5% sensitivity and 70.2% specificity.
Conclusions: Strain decreased from endocardium to epicardium within 48 h after P-PCI in STEMI. Myocardial function was lower in LVR group. Longitudinal epicardial strain could be employed as an independent predictor of LVR after STEMI.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Detecting Hemorrhagic Myocardial Infarction With 3.0-T CMR: Insights Into Spatial Manifestation, Time-Dependence, and Optimal Acquisitions.
JACC Cardiovasc Imaging
January 2025
Department of Radiology and Imaging Sciences and Krannert Cardiovascular Research Center, Indiana University School of Medicine, Indianapolis, Indiana, USA. Electronic address:
Background: Hemorrhagic myocardial infarction (hMI) can rapidly diminish the benefits of reperfusion therapy and direct the heart toward chronic heart failure. T2∗ cardiac magnetic resonance (CMR) is the reference standard for detecting hMI. However, the lack of clarity around the earliest time point for detection, time-dependent changes in hemorrhage volume, and the optimal methods for detection can limit the development of strategies to manage hMI.
View Article and Find Full Text PDFSuccessful Intravascular Ultrasound-Guided Shockwave Intravascular Lithotripsy for a Severely Calcified and Resistant Proximal Left Anterior Descending Coronary Artery Lesion in a Patient with ST-Segment Elevation Myocardial Infarction.
Turk Kardiyol Dern Ars
January 2025
12th Cardiology Department, Hippokration Hospital, Medical School, Aristotle University of Thessaloniki, Greece.
Evaluation of LRP6, SFRP3, and DVL1 Protein Concentrations in Serum of Patients with Gastroenteropancreatic or Bronchopulmonary Neuroendocrine Tumors.
Cancers (Basel)
December 2024
Department of Medical and Molecular Biology, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, 19 Jordana St., 41-808 Zabrze, Poland.
Neuroendocrine tumors are a diverse group of tumors predominantly found in the gastrointestinal tract or respiratory system. : This retrospective study aimed to measure the serum concentrations of LRP6 (low-density lipoprotein receptor-related protein 6), SFRP3 (secreted frizzled-related protein 3), and DVL1 (segment polarity protein dishevelled homolog) using the ELISA method in patients with NETs (N = 80) and a control group (N = 62). We evaluated the results against various demographic, clinicopathological, and biochemical characteristics.
View Article and Find Full Text PDFUnlocking Consumer Preferences: Sensory Descriptors Driving Greek Yogurt Acceptance and Innovation.
Foods
January 2025
Independent Researcher, White Plains, NY 10604, USA.
Greek yogurt, a traditional food with roots in Ancient Greece, Mesopotamia, and Central Asia, has become a dietary staple worldwide due to its creamy texture, distinct flavor, and rich nutritional profile. The contemporary emphasis on health and wellness has elevated Greek yogurt as a functional food, recognized for its high protein content and bioavailable probiotics that support overall health. This study investigates the sensory attributes evaluated by a panel of 22 trained assessors and the consumer preferences driving the acceptance of Greek yogurt formulations.
View Article and Find Full Text PDFNanoscale Characterization of Interaction of Nucleosomes with H1 Linker Histone.
Int J Mol Sci
December 2024
Department of Pharmaceutical Sciences, University of Nebraska Medical Center, Omaha, NE 68198-6025, USA.
In eukaryotic nuclei, DNA is wrapped around an octamer of core histones to form nucleosomes. H1 binds to the linker DNA of nucleosome to form the chromatosome, the next structural unit of chromatin. Structural features on individual chromatosomes contribute to chromatin structure, but not fully characterized.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!