Introduction: Dependent erythema or rubor is an erythematous discoloration of the limbs, most commonly associated with peripheral artery disease. We present a case of florid dependent erythema, associated with additional autonomic symptoms.
Methods: Examination and full workup of a 16-year-old healthy girl with an 8-year history of dependent erythema, chronic diarrhea, and mild hyperhidrosis. A literature search was performed to review any similar cases and generate a differential diagnosis.
Results: Examination of our patient showed symmetrical, asymptomatic fiery to dusky erythematous patches of the lower legs and feet, with intermittent areas of pallor. These florid changes occurred with erect posture. Resolution to near normal occurred within minutes when the patient was in the supine position. Full physical examination revealed mild erythema and hyperhidrosis of the hands.
Conclusions: To our knowledge, there have been no reports of painless dependent rubor associated with sympathetic dysfunction. Literature search reports a few cases of gravitational erythema and angiodyskinesia. This case presentation is most likely part of the spectrum of dependent erythema and may shed light on the underlying aetiology.
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http://dx.doi.org/10.1177/1203475417714801 | DOI Listing |
Cureus
November 2024
Dermatology, Maharishi Markandeshwar Institute of Medical Sciences and Research, Ambala, IND.
Background Topical steroid-dependent or damaged face (TSDF) is a common condition where the widespread availability of over-the-counter topical corticosteroid (TCS)-containing products leads to their misuse and addiction. Prolonged use of these steroids on the face can result in significant side effects. Early diagnosis and cessation of steroid use are important.
View Article and Find Full Text PDFJ Cosmet Dermatol
December 2024
Department of Plastic Surgery, Affiliated Calmette Hospital of Kunming Medical University, Kunming, China.
Background: The Yunnan-Guizhou Plateau's high-altitude setting is characterized by intense solar ultraviolet radiation, a significant environmental stressor that frequently leads to skin barrier damage. This damage presents clinically as erythema, itching, and desquamation, underscoring the need for effective reparative interventions.
Aims: The objective of this study was to assess the therapeutic efficacy of a novel treatment protocol that integrates non-crosslinked hyaluronic acid (HA) injection with microneedle application of human epidermal growth factor (hEGF) for the restoration of skin barrier function in regions of high altitude.
Am J Transl Res
November 2024
Department of Dermatology, Guangdong Provincial Hospital of Chinese Medicine Guangzhou 510120, Guangdong, China.
Background: Sulfur cream is reported to relieve itching and treat skin diseases caused by bacterial, fungal, and scabies infections. However, there is limited data on the efficacy of sulfur cream blowing and parching combined with compound ketoconazole ointment (ketoconazole, clobetasol propionate, and neomycin sulfate) in curing palmoplantar keratotic eczema. This prospective study proposed to investigate the clinical efficacy of sulfur cream on people who suffer with palmoplantar keratotic eczema.
View Article and Find Full Text PDFRev Fac Cien Med Univ Nac Cordoba
December 2024
Universidad Nacional de Córdoba.
Introduction: parvovirus B19 (B19V) infection during pregnancy can be transmitted to the fetus and cause serious complications such as fetal hydrops and stillbirth. The preexistence of specific IgG prevents vertical transmission. Seroprevalence in fertile age is variable (50-70%) and depends on the region/viral circulation, in addition to factors such as maternal age and frequent exposure to children.
View Article and Find Full Text PDFRespir Med Case Rep
November 2024
2nd Chair of Internal Medicine, Faculty of Medicine, Jagiellonian University Medical College, Macieja Jakubowskiego 2, 30-688, Kraków, Poland.
Dupilumab is a monoclonal antibody that has recently been introduced for the treatment of asthma. It has the potential to significantly alter the progression and severity of T2 -dependent diseases, including severe asthma. However, dupilumab can cause transient hypereosinophilia.
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