Neural Manifolds for the Control of Movement.

Neuron

Department of Physiology, Northwestern University, Chicago, IL 60611, USA; Department of Physics and Astronomy, Northwestern University, Evanston, IL 60208, USA. Electronic address:

Published: June 2017

The analysis of neural dynamics in several brain cortices has consistently uncovered low-dimensional manifolds that capture a significant fraction of neural variability. These neural manifolds are spanned by specific patterns of correlated neural activity, the "neural modes." We discuss a model for neural control of movement in which the time-dependent activation of these neural modes is the generator of motor behavior. This manifold-based view of motor cortex may lead to a better understanding of how the brain controls movement.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122849PMC
http://dx.doi.org/10.1016/j.neuron.2017.05.025DOI Listing

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