To summarise the surgical advances and evolution of small gauge vitrectomy and discuss its principles and application in modern vitreoretinal surgery. The advent of microincisional vitrectomy systems (MIVS) has created a paradigm shift away from twenty-gauge vitrectomy systems, which have been the gold standard in the surgical management of vitreoretinal diseases for over thirty years. Advances in biomedical engineering and surgical techniques have overcome the technical hurdles of shifting to smaller gauge instrumentation and sutureless surgery, improving surgical capabilities and expanding the indications for MIVS.
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http://dx.doi.org/10.1155/2017/6285869 | DOI Listing |
Retina
October 2024
Tianjin Key Laboratory of Retinal Functions and Diseases, Tianjin Branch of National Clinical Research Center for Ocular Disease, Eye Institute and School of Optometry, Tianjin Medical University Eye Hospital, Tianjin 384300, China.
Purpose: To describe a novel surgical approach for treating patients diagnosed with severe idiopathic epiretinal membranes (iERM) featuring ectopic intrafoveal layers (EIFL).
Method: A retrospective, interventional case series was conducted involving eight cases of iERM with EIFL. The technique involved a 27-gauge vitrectomy, removal of all vitreous adhesions, and injection of approximately 100μl sub-retinal balanced salt solution (BSS) using a 41-gauge subretinal needle, creating 3-4 localized bleb-like elevations around the folded retina to loosen it.
Equine Vet J
December 2024
Hartpury University, Equestrian Performance Research Centre, Gloucester, UK.
Background: Noseband adjustment should avoid discomfort and allow some jaw movement.
Objectives: To determine pressure beneath a cavesson noseband at five tightness levels during standing and chewing. It was hypothesised that increased noseband tightness is associated with increases in nasal and mandibular pressures while standing and chewing, accompanied by increases in eye temperature and blink rate.
Int J Biol Macromol
December 2024
School of Chemistry and Chemical Engineering, Guangxi Key Laboratory of Petrochemical Resource Processing and Process Intensification Technology, Guangxi University, Nanning 530004, PR China. Electronic address:
Conductive hydrogels are utilized in flexible sensors due to their high-water content, excellent elasticity, and shape controllability. However, the sharp increase in resistance of this material under enormous strain leads to instability in the sensing process. This study presents a straightforward method for creating a stable, recyclable, hybrid ionic-electronic conductive (HIEC) hydrogel via a simple one-pot strategy using polyvinyl alcohol (PVA), bagasse cellulose nanofibrils (CNF), and graphene(G) with sodium dodecylbenzene sulfonate (SDBS).
View Article and Find Full Text PDFJ Colloid Interface Sci
December 2024
Department of Orthopaedic Surgery, Sichuan Provincial People's Hospital, Sichuan Academy of Medical Science, Affiliated Hospital of University of Electronic Science and Technology, Chengdu 610072, China. Electronic address:
Strain sensors with high sensitivity and wide detection range are essential for meeting diverse applications, such as precisely monitoring the movement of patients with bone defects during rehabilitation. However, extending the sensing range without compromising sensitivity, particularly for small strains, remains a significant challenge for flexible sensors. Here, a strain redistribution strategy was employed to achieve wide-range and high-sensitivity monitoring of natural rubber (NR)-based sensors.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
School of Engineering and Applied Sciences (SEAS), Harvard University, Cambridge, Massachusetts 02138, United States.
The clinical use of small interfering RNA (siRNA) and antisense oligonucleotides often requires invasive routes of administration, including intrathecal or intraocular injection. Additionally, these treatments often necessitate repeated injections. While nanoparticle formulation and chemical modifications have extended siRNA therapeutic durability, challenges persist, such as the side effects of bolus injections with high toxicity and maximum exposure in the acute phase.
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